“Implant Solutions for Complex Cases: Solutions with Grafting” – Posterior Vertical Bone Regeneration Techniques

Key points

  • •

    The absence of mechanical stimulation from teeth leads to reduced osteoblastic activity, activation of osteoclasts, and alveolar ridge resorption, with up to 50% dimensional loss in 6 to 12 months postextraction.

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    Bone loss complicates implant placement, often requiring augmentation procedures such as guided bone regeneration (GBR) or bone grafting to restore adequate support.

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    Horizontal augmentation is more predictable, while vertical augmentation is highly technique-sensitive, less vascularized, and carries higher complication (20%) and re-intervention (25%) rates.

  • •

    Autogenous bone remains the gold standard for vertical augmentation due to its osteogenic potential and stability, though modern biomaterials and membranes also enable conservative GBR approaches.

  • •

    Vertical grafting demands significant soft tissue advancement for closure, often leading to vestibular flattening, additional grafting procedures, longer treatment times, and increased patient morbidity.

Abbreviations

d-PTFE dense polytetrafluoroethylene
GBR guided bone regeneration
KM keratinized mucosa
PTFE polytetrafluoroethylene
RP retromolar pad
SBBT split bone block technique
VGBR vertical guided bone regeneration

Introduction

The alveolar process is a delicate anatomic structure crucial in oral rehabilitation involving dental implants. When teeth are present, mechanical loading is detected by osteocytes, which release signaling molecules to promote osteoblast activity, maintaining bone turnover to support tooth function. However, after tooth loss, the absence of a tooth root to transfer mechanical stimulation leads to decreased osteoblastic activity and activation of osteoclasts, resulting in bone resorption. Consequently, the alveolar ridge undergoes significant dimensional changes, , with reductions of up to 50% in height and width within 6 to 12 months after extraction.

As a consequence, when edentulous patients require replacement with dental implants, these deficiencies can lead to complex clinical situations for implant placement and treatment planning. These cases often necessitate bone augmentation procedures, either staged or performed simultaneously with implant placement. Although dental implants serve as an ideal tooth replacement that can also provide this mechanical stimulation, the damage they are capable of causing if they fail because of peri-implant diseases or need to be removed for other reasons such as unfavorable aesthetics can be devastating. Such situations can result in significant defects that require advanced augmentation procedures. Given the increasing age of the population, the prolonged retention of periodontal involvement, and the high prevalence of peri-implant diseases, these defects are becoming more common in current implantology practices. Furthermore, even in cases without major tissue loss, placing implants in their prosthetically guided position often necessitates performing guided bone regeneration (GBR) to create the critical buccal bone thickness to ensure stable, long-term peri-implant bone support.

Although bone augmentation procedures are highly technique sensitive, systematic reviews have shown that, when performed correctly, it can yield an average of 4.28 mm in horizontal as well as 4.16 mm in vertical bone regeneration. However, achieving predictable vertical bone regeneration poses unique challenges compared with horizontal augmentation (Urban and colleagues 2019). For this purpose, several techniques have been proposed. The most common involves using autologous bone grafts, originally described as the gold standard for vertical defects. Variations on this approach include the Khoury technique, the wafer technique, and the split bone block technique (SBBT). , However, current improved biomaterials and membranes have allowed slightly more conservative approaches like GBR to also obtain good results augmenting bone in a vertical direction. Regardless of the used surgical technique, these cases come with a heightened degree of technique sensitivity and more complex surgical approaches, both of which add to an increased likelihood of complications, which have a reported average of 20%, as well as patient morbidity and need for repeat intervention in up to 25% of cases.

In addition to these notable challenges associated with vertical augmentation, the procedure often resulted in greater morbidity because of the frequent need for a second surgical site to harvest autologous bone. In contrast to horizontal augmentation, which typically occurs within or adjacent to bony contours with a more robust vascular supply, vertical augmentation typically extends beyond the alveolar crest and lacks the benefit of a vascularized bony housing. As a result, vertical grafts must rely on a more limited blood supply. To address this challenge, the use of autogenous bone is frequently recommended. Autogenous bone contains a rich supply of osteogenic cells and growth factors and facilitates blood vessel formation. Moreover, because of the lack of osseous wall containment in most vertical defects, reinforcing the graft with autogenous bone plates offers superior structural stability, maintaining space for new bone development while promoting reliable and predictable regeneration. If the GBR approach is used, titanium reinforced nonresorbable membranes are commonly used to provide increased graft stability and containment during healing. ,

Because of the larger volume of augmentation in vertical grafting, these cases also require a significant amount of soft tissue advancement to provide a primary closure and tension-free healing in a closed environment. In advanced cases, this can lead to significant repositioning of the mucogingival junction and subsequent obliteration of the vestibule, which often necessitates further soft tissue grafting in a another intervention. From the patient’s perspective, these additional surgeries add, once again, significant morbidity to the overall treatment, and increase the total treatment time, both of which have impacts on quality of life.

Although the added complexities of vertical augmentation may seem daunting, successfully regenerating the vertical dimensions of the alveolar crest can allow for ideal implant positioning, limiting prosthetic complications due to large crown height spaces, which can also allow patients to have more favorable oral hygiene and reduce possible biological and biomechanical complications. ,

In a specific subset of patients, this may even reduce the overall morbidity of a patient’s treatment plan, as many patients may be on a path to total edentulism if vertical augmentation cannot be achieved. In the case of full arch rehabilitations, a patient is typically planned for an FP3 prosthesis when there has been a history of vertical resorption of the alveolar crest. In these circumstances, the entire remaining arch will often be reduced to the level of the vertical defect. The rationale for this treatment is that vertical augmentation procedures are unpredictable and have a high degree of morbidity. However, the demolition of a patient’s entire alveolar process should not be taken lightly. Especially in the case of younger patients in whom implants will be needed to provide decades of function, this ostecomy may result in a nearly impossible rehabilitation should the implants fail in the future. Thus, being able to manage these severe vertical defects, which are becoming more common in modern-day clinical practice, should be within the abilities of an oral surgeon who performs dental implant rehabilitations.

Thus, the aim of this article was to showcase certain clinical scenarios of severe vertical bone defects and their resolution, in order to enhance further understanding of the complexity that they present, and provide different advance bone grafting techniques to manage them. This hopefully encourages readers to apply insights from these case scenarios in order to improve their clinical practice.

Case 1: conventional vertical guided bone regeneration with titanium-reinforced dense polytetrafluoroethylene (d-PTFE)

Case description

A 76-year-old man presented with a complex 12 mm vertical defect in the lower left posterior mandible secondary to severe periimplantitis, combined with a limited band of keratinized mucosa (KM) (approximately 1–2 mm) ( Fig. 1 A–C ). Although some advocate performing a free gingival graft before GBR to enhance KM and flap stability, in this case an intact periosteum was deemed sufficient to provide the necessary stability of the flap margins. A 5 mm discrepancy between the distal and mesial bone levels at tooth #33 was also present. To achieve optimal bone peak height and an ideal restorative outcome, the decision was made to extract the canine and perform vertical bone regeneration in the region of #33 to #36 using a titanium-reinforced dense polytetrafluoroethylene (Ti-dPTFE) membrane in conjunction with an autogenous bone/xenograft mixture.

Fig. 1

( A ) Baseline panoramic radiograph, showing the vertical defect in the third quadrant, left by an infection around previously placed implants. ( B ) Baseline buccal intraoral situation of the vertical bone defect, showing the loss of attachment distal to the canine. ( C ) Baseline occlusal intraoral situation of the bone defect, showing minimal keratinized mucosa after healing of the explantations. ( D ) Flap elevation and exposure of the inferior alveolar nerve cautiously to avoid any neurologic damage. ( E ) Canine extraction and presence of a 10 mm vertical bone defect after flap elevation. ( F ) Flap release and mobilization without tension, which is mandatory to avoid future complications, such as the exposure of the membrane. ( G ) Autogenous bone collection from the same surgical site by means of a trephine. ( H ) The Ti-dPTFE membrane was stabilized lingually with fixation pins to stabilize the graft. ( I ) The autogenous graft was turned into bone chips and mixed with 20% of xenograft. ( J ) Buccal membrane stabilization with fixation pins to hold and stretch the membrane preventing any micromovement, while avoiding contact with neigboring anatomic structures. ( K ) Tension-free wound closure with PTFE, by means of a combination of a layer of horizontal mattress sutures and a second layer of simple sutures. ( L ) Uneventful healing after more than 6 months. ( M ) Buccal intrasurgical situation at re-entry surgery, 9 months after GBR. ( N ) Occlusal intrasurgical situation at re-entry surgery, showing perfect adaptation of the membrane. ( O ) Occlusal intrasurgical situation after membrane removal, showing newly formed and vascularized bone. ( P ) Buccal intrasurgical situation after membrane removal, with the vertical bony defect completely restored. ( Q ) Guided implant placement of 3 bone-level dental implants. ( R ) Intraoral situation, showing clinical stability 1 year after prosthetic loading. ( S ) Panoramic radiograph, showing radiographic stability 1 year after prosthetic loading.

Flap and incision design

Given the minimal KM, the crestal incision was carefully placed within the available 1 to 2 mm of KM. Vertical releasing incisions were positioned mesial to #31—sparing the papilla between #31 and #41 for later flap stabilization—and distal to the planned GBR site. On the buccal aspect, a full-thickness flap was elevated to fully expose the defect and identify the mental nerve. Its location was marked on the crest with a sterile pencil to facilitate awareness throughout the procedure ( Fig. 1 D, E). A continuous periosteal releasing incision was then made, connecting the vertical incisions and leaving a coronal cuff of at least 6 mm of intact periosteum. This margin permitted the placement of horizontal mattress sutures approximately 4 mm from the wound margin, ensuring that the suture line was entirely within the robust periosteum for optimal flap stability. Internally, a blunt instrument was used to gently elongate the collagen fibers, enhancing flap release and achieving a tension-free, passive primary closure while minimizing any risk of nerve trauma ( Fig. 1 F).

Lingual flap management

Lingual flap preparation was performed, to aid in tension-free closure. The lingual tissues were carefully elevated using a periosteal instrument to gently reflect the retromolar pad (RP) from the bone, pulling it in a coronal direction to incorporate it into the flap. After identifying the mylohyoid muscle insertion, a blunt instrument was used to displace the soft tissue superior to the muscle laterally, preserving the muscle’s integrity. At the premolar region, a semiblunt periosteal release was performed using a number 15 blade at a rotated perpendicular angle with a sweeping motion. This provided the necessary flexibility for coronal flap advancement while minimizing the risk of postoperative dehiscence.

Graft placement and membrane stabilization

Autogenous bone was harvested from within and around the defect using a trephine, which not only supplied a generous volume of bone but also stimulated the regional acceleratory phenomenon ( Fig. 1 G). The harvested bone (constituting approximately 70% to 80% of the graft volume) was mixed with a xenograft to enhance volume stability for vertical augmentation. The Ti-dPTFE membrane was first secured on the lingual aspect with tacks to create a stable wall against which the graft could be supported. The 80:20 autogenous-to-xenograft mixture was then densely packed into the defect, and the membrane was folded over the graft. It was secured with 2 tacks distally and 1 tack mesially. Before placement of the final pin, the membrane was trimmed carefully to avoid exerting pressure on the mental nerve, and then stretched over the graft to optimize stability ( Fig. 1 H–J).

Wound closure and postoperative protocol

Closure was achieved using PTFE sutures in a 2-layer technique over the crest; horizontal mattress sutures placed approximately 4 mm from the wound margin (within the robust periosteum) ensured intimate flap contact and vascular integration, followed by single interrupted sutures to approximate the wound edges. Additional single interrupted sutures were used in the vertical releasing areas and interpapillary regions ( Fig. 1 K). After a 9-month healing period ( Fig. 1 L), re-entry surgery confirmed complete regeneration of the defect ( Fig. 1 M–P). Guided implant surgery was then performed, with 3 implants placed 1 mm subcrestally ( Fig. 1 Q), and the final restorative phase included a free gingival graft and vestibuloplasty on the buccal side to secure adequate keratinized mucosa for long-term stability ( Fig. 1 R, S).

Case 2: posterior mandible vertical guided bone regeneration with simultaneous implant placement

Case description

A 59-year-old woman presented with a severe vertical defect in the lower right mandible after years of wearing a removable partial denture ( Fig. 2 A). There was a 3 mm discrepancy between the mesial and distal bone peaks on tooth #44, so the decision was made to extract the tooth to take advantage of the mesial bone peak. This was performed simultaneously to implant placement and vertical ridge augmentation using a d-PTFE membrane and a 50:50 blend of allograft and autograft ( Fig. 2 B).

Fig. 2

( A ) Baseline panoramic radiograph, showing the vertical defect in the fourth quadrant. ( B ) Baseline intraoral view of the vertical defect, combined with a decayed and fractured tooth #44. ( C ) Buccal flap release and mobilization, until overcoming the incisal edge of the neighboring teeth. ( D ) Guided implant placement with a static guide, and extraction of #4.4. ( E ) Implants were placed supracrestally into a prosthodontically driven position, planning to be at least 1 mm under the future bone crest after bone augmentation. ( F ) Lingual membrane fixation, and autogenous bone was mixed with allograft in a 50:50 proportion. ( G ) Ti-dPTFE membrane was stabilized buccally and lingually using tacks and microscrews, and making sure it did not contact the adjacent teeth. ( H ) Tension-free wound closure with PTFE by a combination of horizontal mattress and simple sutures. ( I ) Uneventful healing 6 months after bone augmentation. ( J ) Surgical re-entry and membrane exposure 9 months after GBR, showing perfect adaptation of the membrane. ( K ) After membrane removal, the implants were completely covered by newly formed and vascularized bone. ( L ) Implants were exposed and multiunit abutments connected to them. ( M ) Final favorable situation of hard and soft tissue volume, after the bone augmentation and the free gingival graft. ( N ) Panoramic radiograph after membrane removal and connection of the multiunit abutments to the implants. ( O ) Stable clinical situation 1 year after loading. ( P ) Stable radiographic situation 1 year after loading.

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Sep 27, 2026 | Posted by in Oral and Maxillofacial Surgery | Comments Off on “Implant Solutions for Complex Cases: Solutions with Grafting” – Posterior Vertical Bone Regeneration Techniques

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