Background and objectives : Most retrospective studies on Odontogenic tumours (OTs) have left the question of relative frequency and incidence of OTs unanswered. We sought to determine the relative frequency and incidence of OTs in the Nigerian population, over four years; as an update to a year prospective study presented at 20th ICOMS.

Methods : Prospective data collection from January 2009 to December 2012 from all centres involved in the management of OTs in Nigeria. Data collection tool was a structured questionnaire designed to obtain demographic and clinico-pathologic information on all cases of OTs presenting and diagnosed at the centres. Data was entered into SPSS statistical soft ware and analysed using simple descriptive statistics.

Results : 448 patients’ information was obtained. They were 237 males and 211 females, aged 7–89years. Their mean age (SD) was 32.69(14.48). An estimated national incidence of 2.63 per million population was obtained. 86.5% of lesions were in the mandible, while 13.5% were in the maxilla. Ameloblastoma had the highest relative frequency constituting (356/448) 79.5% with an incidence rate of 2.09 per million population; followed by Odontogenic myxoma (17/448)3.8%.

Conclusion : Incidence of OTs vary in African countries but ameloblastoma appears to be most prevalent.