Objectives: Mesenchymal stem cells (MSCs) isolated from various tissues have been used for clinical application in tissue engineering and regenerative medicine. To date, the most common source of MSCs has…
Introduction: Periodontitis is the most common cause for tooth loss in adults and advanced types affect 10–15% of adults worldwide. The attempts to save tooth and regenerate periodontal apparatus including…
Stem cell therapy for tissue guided bone regeneration is a promising approach and widely studied in maxillofacial surgery i.e. bone regeneration and implant surgery. Aim: The concept using mesenchymal stem…
Aim/objective/purpose: To present a novel guided bone regeneration (GBR) concept that consists of combining Boneject ® (a biomaterial containing atelocollagen and bovine hydroxyapatite particles) with thermoplastic, bioresorbable plates (DeltaSystem ®…
Objectives: The efficacy of rhBMP2 with bone grafts (rhBMP2-BG) in promoting adequate bone formation within critical size defects is documented. However, the efficacy in treating jaw resection (including segmental) has…
Purpose: To analyze effect of an alternating distraction–compression protocol over conventional distraction osteogenesis (DO) protocol on new bone formation. Materials and methods: Eighteen rabbits underwent bilateral mandibular corticostomy, custom-made distractor…
Aseptic osteolysis is a main cause of loosening of orthopaedic implant failures. The wear debris derived from polymers (UHWMPE) and/or metals of implants (Ti) elicit primary inflammatory and secondary osteolytic…
Microvascular anastomosis is a critical step in the survival of free transferred tissue. It depends on a technically sound anastomosis between donor and recipient site blood vessels. This is typically…
Objective: To reconstruct Mandibular defect using tissue engineering bone with BMSCs cell sheets and investigate the effect of cell sheets on osteogenesis. Methods: Bone marrow stem cells were isolated and…
Purpose: To investigate the effect of BMSCs cell sheet on the formation of functional tissue-engineered bone in dogs. Method: BMSCs were derived from dog bone marrow and cell sheets were…
