The History of Sleep Medicine
Sleep medicine as it is known today actually started as research and scientific study, not as clinical medicine. When one considers that sleep medicine today is in its infancy, it…
Therapeutic Potential of Mesenchymal Stem Cells for Oral and Systemic Diseases
Mesenchymal stem cells (MSCs) are adult stem cells whose self-renewal, multipotency, and immunosuppressive functions have been investigated for therapeutic applications. MSCs have used for various systemic organ regenerative therapies, allowing…
Outcomes of Regenerative Endodontic Procedures
The use of regenerative endodontic techniques holds great promise for the treatment of immature teeth with necrotic pulp tissue. Several published case reports and case series have demonstrated radiographic evidence…
Regenerative Endodontics
Regenerative endodontics has encountered substantial challenges toward clinical translation. The adoption by the American Dental Association of evoked pulp bleeding in immature permanent teeth is an important step for regenerative…
Clinical Considerations for Regenerative Endodontic Procedures
The management of a tooth with incomplete root maturation and a necrotic pulp is an endodontic and a restorative challenge. Apexification procedures alone leave the tooth in a weakened state…
Regenerative Endodontics and Tissue Engineering
The work performed by researchers in regenerative endodontics and tissue engineering over the last decades has been superb; however, many questions remain to be answered. The basic biologic mechanisms must…
Harnessing the Natural Regenerative Potential of the Dental Pulp
Biological solutions for the repair and regeneration of the dental tissues offer significant potential for improved clinical treatment outcomes. Translation of dental tissue-engineering approaches to the clinic will make considerable…
Constructs and Scaffolds Employed to Regenerate Dental Tissue
Dental tissue injury and regeneration affects the daily lives of almost everyone. Tissue engineering is emerging as a promising therapy to regenerate missing teeth and dental tissues. The aim of…
Regenerative Therapy
Periodontal and endodontic diseases are inflammatory responses leading to periodontal and pulpal tissue loss. Regenerative therapies aim to restore the lost structures to vitality and function. Various materials and treatments…
Dental Stem Cells and Their Sources
The search for more accessible mesenchymal stem cells than those found in bone marrow has propelled interest in dental tissues. Human dental stem/progenitor cells (collectively termed dental stem cells [DSCs])…
