Allergic Reactions to Local Anesthetic Formulations
True allergic reactions to local anesthetics are rare adverse reactions. At the most, they represent less than 1% of all adverse local anesthetic reactions. When true allergic reactions have been…
Long-Acting Local Anesthetics and Perioperative Pain Management
Although the use of long-acting local anesthetics has become a useful therapeutic approach for managing peri- and postoperative pain, recent evidence reveals unexpected outcomes. This article reviews the clinical use…
Efficacy of Articaine Formulations: Quantitative Reviews
In 2000, the US Food and Drug Administration (FDA) approved the use of 4% articaine with epinephrine 1:100,000, and with epinephrine 1:200,000 in 2006. Articaine has been commonly compared with…
Infiltration Anesthesia in the Mandible
Infiltration is preferred to regional block techniques in the maxilla as the former offers a number of advantages. This paper considers the evidence for the efficacy of infiltration anesthesia in…
The Use of Local Anesthetic Agents in Medicine
Local anesthetics are commonly used in both dentistry and medicine. These drugs are also used in some office-based medical practices. Except for minor procedures, most physicians who require complicated nerve…
Local Anesthetics: Pharmacology and Toxicity
The development of safe and effective local anesthetic agents has possibly been the most important advancement in dental science to occur in the last century. The agents currently available in…
