The use of platelet-rich-plasma may provide a new and improved treatment option for early temporomandibular joint (TMJ) osteoarthritis. However, there are no studies on its use in TMJ arthritis in the literature. The present study compares 30 early onset TMJ OA patients divided equally into 3 groups who had experienced no pain reduction following conservative and miminally invasive arthrocentesis and arthroscopy treatment. All patients had retrodiscitis and synovitis on arthroscopic examination and were without systemic joint disease, septic, or autoimmune arthritis. Only patients with unilateral TMJ symptoms were included in this study. Pain intensity was recorded for each patient using a 0–10 VAS scale. Maximum interincisal opening (MIO) was also recorded. This assessment was performed at the pretreatment and then at an examination 3 months after administration of 2 intra-articular applications of autologous PRP (Group A), 2 intra-articular injections of hyaluronic acid (HA) (Group B), or commencement of conservative therapy only with soft diet and analgetics (Group C). The results after 3 months revealed that intra-articular injection of autologous PRP appeared to be an effective treatment method for patients with early TMJ OA in this study. 70% of the PRP patients (Group A) showed decreased pain. The average pain score before PRP administration was 7, while 3 months after PRP administration the pain score was 3.5.
Platelet-rich plasma in temporomandibular joint osteoarthritis therapy: a 3-month follow-up pilot study
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