Background and objectives : BRONJ seems to be a rising entity in maxillofacial surgery, especially when focusing on oral anti-resorptive therapy. Literature of the past decade focused on diagnosis, prophylaxis…
In accordance to some contemporary scientific literature the incidence of BRONJ in patients receiving IV BPs i.v. ranges from 0.8% to 16%. Different treatment protocols of BRONJ are described in…
In 2003 began to be published the first cases of osteonecrosis of the jaws associated with the administration of intravenous bisphosphonates. The aim of our contribution is to present a…
Bisphosphonates reduce skeletal complications of bone diseases such as osteoporosis and bone metastases. During the last years, the number of patients with bisphosphonate-associated necrosis of the jaw (BP-ONJ) increased. Many…
Background and objectives : Bisphosphonates are used for treatment of bone metastases, multiple myeloma, osteoporosis and other bony diseases. Osteonecrosis of the jaw is a well known potential complication of…
We have proposed our original guidelines for management of patients receiving bisphosphonates (BPs) in 2008, and have managed 666 patients according to our guidelines till February 2013. Patients were classified…
Background and objectives : Since the first description of bisphosphonates related osteonecrosis of the jaw (BRONJ) made in 2003 there has been an increased number of cases described in the…
Background and objectives : Treatment of bisphosphonate (BP)-induced osteonecrosis of the jaws (ONJ) varies from conservative to surgical and there exist no global consensus. Since 2010 we have used a…
Background : Bisphosphonate-related osteonecrosis of the jaw has become a well known problem of rising clinical importance. The treatment is exceptionally hard. Fluorescence guided bone resection is a promising technique…
Background and objetives : Bisphosphonates are antiresorptive drug fully accepted for the treatment of metastatic bone disease, osteoporosis and other bone diseases. In 2003, Marx published 36 patients with exposed…
