Background and objectives: Gemcitabine (GEM) is a pyrimidine nucleoside analogue that is a new chemotherapeutic agent used for treating various cancers. Because accumulating evidence indicates that GEM may activate host…
Rationale: The TNM system for classification of Head and neck malignant tumours is a universally accepted, widely used, staging method which helps clinicians and researchers to choose from treatment options,…
Introduction: In the UK 5000–7000 head and neck cancer cases are diagnosed annually. Only 50 per cent are curable. The remaining terminal cases are managed by palliative care services in…
Background and objective: We have already demonstrated that post-operative concentration of salivary interleukin-6 (IL-6) may predict early locoregional recurrence in oral squamous cell carcinoma (OSCC) (Head & Neck; 2012). This…
Background and objectives: The most important prognostic factor for survival in tongue cancer is the presence of cervical lymph node metastases. Their presence determines the therapeutic strategy. 20–30% of stages…
Introduction: In the oral cavity the most common malignant lesion is Squamous cell Carcinoma. Though the primary modality of treatment for patients with oral cavity cancer remains surgical resection, reconstruction…
Background: Radiation therapy is often part of treatment of head and neck malignancies. After radiotherapy patients are at risk to develop osteoradionecrosis. The development of osteoradionecrosis is unpredictable and has…
Background and objectives: Patients with major salivary gland pathology may present with a suspected mass, diffuse glandular enlargement or symptoms of obstruction and inflammation. Various imaging modalities are available for…
Helicobacter pylori is a microaerophilic bacteria, gram-negative, spiral shaped and mobile which is believed to be one of the main factors responsible for gastritis, gastric ulcers and gastric cancer. H…
Introduction: Transoral robotic surgery (TORS) has been advocated as a means to de-intensify adjuvant therapy and to improve functional treatment outcomes in advanced stage oropharynx cancer. The purpose of this…
