Syndromes Affecting the Central Nervous System
Key points • Many syndromes affecting the central nervous system (CNS) demonstrate both intraoral signs as well as head and neck manifestations. • Their causes include, but are not limited…
Hamartoneoplastic Syndromes
Key points • Hamartomas are benign malformations presenting as an excess of normal tissue within the tissue of origin. • Although some syndromes show a clear genetic transmission, the underlying…
Clefting Syndromes
Key points • There are over 500 syndromes with clefting as part of the phenotype. • An understanding of sequence is needed to effectively manage patients with clefting disorders. •…
Branchial Arch Syndromes
Key points • Branchial arch syndromes present with variable expressivity. • Management necessitates a multidisciplinary approach. • Features corroborate a disorder with first and second branchial arch derivatives. • Treatment…
Syndromes Affecting Skin and Mucosa
Key points • Ehlers-Danlos syndromes are a heterogeneous group of disorders characterized by abnormal formation of collagen or molecules related to collagen synthesis, abnormalities in the matrix glycoprotein tenascin, and…
Metabolic and Autoimmune Syndromes
Key points • Genetic alterations can cause physiologic responses resulting in systemic and metabolic complications. • These complications can cause significant deficits, as in Hurler and Williams syndromes, which can…
Syndromes Affecting Bone
Key points • Look beyond the primary jaw pathology for clues of syndromic involvement. Observe the skin, and always consider extrafacial skeletal involvement. • Study Gorlin’s Syndromes of the Head…
Craniosynostosis Syndromes
Key points • Craniosynostosis syndromes have wide phenotypic variability. Understanding of the underlying genetic causes continues to develop. • Children with these syndromes are best managed at a multidisciplinary craniofacial…
Syndromes of the Head and Neck
Dean M. DeLuke, DDS, MBA, Editor The purpose of this issue of the Atlas of the Oral and Maxillofacial Surgery Clinics of North America is to serve as an aid…
Dedication
To: Dr. Dominick J. DeLuke and Dr. Leon Eisenbud. In recognition of their many contributions to the profession, and with thanks for allowing me to “see a little further by…
