Skeletal biotype in TMJ Osteoarthritis
TMJ Osteoarthritis (OA) is defined as a chronic and degenerative disease with an important yet secondary inflammatory component and is the result of an unbalance anabolic and catabolic metabolism inside…
Synovitis in internal derangement of the temporomandibular joint: correlation between primary and secondary arthroscopic findings and final outcome
Background and aim of study: To evaluate the effect of primary diagnostic arthroscopic procedures on TMJ Synovitis when compared to secondary surgical arthroscopic findings and its impact on the final…
Effect of different concentrations of alendronate on the viability and proliferation of different cell types
Introduction: Bisphosphonates have been therapeutically used for the management of lytic bone diseases. Their use has been increased nowadays and besides that associated adverse effects have been amplified. Jaw osteonecrosis…
9 Years follow up of TMJ prosthetic reconstruction
Patients that have undergone to total TMJ prosthetic reconstruction for different reasons, such as trauma, degenerative diseases and cysts. TMJ total prosthetic reconstruction turned up to be a wonderful manner…
Factors influencing bone formation capacity of human embryonic stem cell-derived osteoblast-like cells
To apply human embryonic stem cells (hESCs) as a source of osteoblast-like cells (hESC-OS), factors influencing bone formation potential of hESC-OS need to be evaluated. Aims: The study aimed to…
Human mesenchymal stem cells derived from dental pulp. Alternative source for the regenerative medicine based therapy
Objectives: Mesenchymal stem cells (MSCs) isolated from various tissues have been used for clinical application in tissue engineering and regenerative medicine. To date, the most common source of MSCs has…
Efficacy of dental stem cell transplantation in the treatment of advanced periodontitis
Introduction: Periodontitis is the most common cause for tooth loss in adults and advanced types affect 10–15% of adults worldwide. The attempts to save tooth and regenerate periodontal apparatus including…
Activated autologous bone marrow for bone tissue engineering in the maxillofacial area: clinical application in preprosthetic implant surgery
Stem cell therapy for tissue guided bone regeneration is a promising approach and widely studied in maxillofacial surgery i.e. bone regeneration and implant surgery. Aim: The concept using mesenchymal stem…
Achieving bone augmentation with hydroxyapatite and thermoplastic polylactic acid plating: a histological study in rats
Aim/objective/purpose: To present a novel guided bone regeneration (GBR) concept that consists of combining Boneject ® (a biomaterial containing atelocollagen and bovine hydroxyapatite particles) with thermoplastic, bioresorbable plates (DeltaSystem ®…
Use of rhBMP2 with bone grafts in pediatric jaw resection cases
Objectives: The efficacy of rhBMP2 with bone grafts (rhBMP2-BG) in promoting adequate bone formation within critical size defects is documented. However, the efficacy in treating jaw resection (including segmental) has…
The effect of alternating tensile & compressive force on new bone formation during distraction osteogenesis on rabbit mandible
Purpose: To analyze effect of an alternating distraction–compression protocol over conventional distraction osteogenesis (DO) protocol on new bone formation. Materials and methods: Eighteen rabbits underwent bilateral mandibular corticostomy, custom-made distractor…
Bone microenvironment associated to wear debris in temporomandibular joint implants: pre-clinical model in mice
Aseptic osteolysis is a main cause of loosening of orthopaedic implant failures. The wear debris derived from polymers (UHWMPE) and/or metals of implants (Ti) elicit primary inflammatory and secondary osteolytic…
A novel method of anastomosing vessels using an intraluminal stent: a proof of principle study
Microvascular anastomosis is a critical step in the survival of free transferred tissue. It depends on a technically sound anastomosis between donor and recipient site blood vessels. This is typically…
A experimental study of reconstructing Mandibular defect using tissue engineering bone with BMSCs cell sheets in dog
Objective: To reconstruct Mandibular defect using tissue engineering bone with BMSCs cell sheets and investigate the effect of cell sheets on osteogenesis. Methods: Bone marrow stem cells were isolated and…
A preliminary study on the application of BMSCs cell sheet on the formation of functional tissue-engineered bone in dogs
Purpose: To investigate the effect of BMSCs cell sheet on the formation of functional tissue-engineered bone in dogs. Method: BMSCs were derived from dog bone marrow and cell sheets were…
Surgical treatment for patients with craniosynostosis. Report of 22 cases
Craniosynostosis is a disease characterized by the early closure of one or more cranial sutures associated to a perpendicular deformity to the suture from overgrowth. It can be found isolated…
Pre and post adenoid/tonsillectomy craniofacial architecture in a group of children with sleep disordered breathing
Introduction: The skeletal craniofacial morphology is the functional reflection of nearby structures and functional conditions to which it is subjected. Obstruction of the upper airway is common in children and…
Internal distraction in craniofacial dysostosis (CFD) to achieve frontofacial advancement
Adequate surgical correction requires an individually staged strategy with respect to severity of the deformity, age and development of the patient. Frontofacial distraction techniques have been recommended for that purpose….
The effect of cranial base surgery on congenital craniofacial deformities
Introduction: The cranial base is a “constructional template” for facial development, normal or abnormal. Craniofacial synostosis involves abnormalities of the sutures of the cranium, the face, and the growth centers…
Coronoid hyperplasia in pediatric patients
Coronoid hyperplasia is a rare condition that is characterized by enlargement of the coronoid process. It causes painless progressive limitation of the mouth opening because of the impaction of the…
