Fig. 9.1 Classical triad of tissue engineering: cells, supporting scaffold and growth factors Fig. 9.2 Current concept of tissue engineering . The cells communicate with its environment with structural, physical,…
Property Co-Cr Ti Au GC Al2O3 YZP PFR FRC Isotropicity + + + + + + + +/− Anisotropicity − − − − − − − +/− Toughness − +/−…
Criterion AECGa ACRa ACR/EULARa Subjective Sicca eye + − Entryb Sicca mouth + − Entryb Objective Ocular signs: Schirmer’s test +…
Fig. 12.1 Healing of aphthous ulcers on the upper labial mucosa following 2 days of treatment with locally applied doxycycline gel (see Ref. 8). The gel was applied to the ulcer…
Fig. 11.1 Frequency (%) of children and adolescents without caries and restorations in 1973, 1983, 1993, 2003, and 2013 11.2.2 Periodontitis and Gingivitis Between 1983 and 2013, there was a…
Fig. 2.1 The classical cycle of investigation, hypothesis and experimentation in clinical research 2.2 What Is Research in Medical and Dental Schools? It can be argued that research in dental…
Fig. 6.1 Immediate implant placement protocol which includes (a) and (b) careful and atraumatic tooth extraction; (c) flapless implant placement in the ideal prosthetically driven position; (d) placement of a…
Fig. 13.1 Hippocrates 460–377 BC Fig. 13.2 Main steps for attaining permit(s) for scientific investigation. In life sciences approval by ethical committee has a central role The need for something broader…
Fig. 8.1 It has been reported that periodontitis increases the risk of cardiometabolic diseases. It also has been proven that smoking or obesity increases periodontitis and that they independently contribute…
Fig. 4.1 Inflammation limited to the gingival margin in a female adult African To effectively manage those “difficult to explain” cases, periodontologists must embrace the shift to the measurement of…
!DOCTYPE html SYSTEM “about:legacy-compat”> © Springer International Publishing AG, part of Springer Nature 2018 Jukka H. Meurman (ed.)Translational Oral Health Researchhttps://doi.org/10.1007/978-3-319-78205-8_7 7. A Critical Reason for Conducting Clinical Trials Is that Results with Humans…
miRNA Regulation periodontally affected tissues Type of immune system affected in periodontitis Mechanism Upregulated Downregulated miR-30e – Yes Innate immune system Inhibits NK cell activation. This downregulation increases NK cell…
Fig. 1.1 This figure depicts the four translational phases in the biomedical research translation continuum (T1–T4) and provides examples of methodological approaches that are used within each phase Most models…
