Histomorfologic and histomorphometric study of bone healing in dry socket condition induced in rats treated with ozonized oil

The aim of this research was to evaluate histologic and morphometric aspects of alveolar wound healing in rats induced to dry socket condition and treated by ozonated sunflower oil and Alveoliten ® . Under general anesthesia 84 female Wistar rats underwent to upper right incisor extraction. 72 animals were induced to alveolar osteitis by adrenalin (1:100,000) intra-alveolar insertion for five minutes. Groups were divided as: GI alveolar osteitis condition treated with sunflower oil; GII: alveolar osteitis condition treated with ozonated oil (87.3 mequiv./kg de peroxide and 0.4 acid); GIII: alveolar osteitis condition treated with Alveoliten ® ; GIV alveolar osteitis condition without any treatment; and GV: incisor extraction without alveolar osteitis neither treatment. Animals were euthanized 2, 7, 14 and 21 days after treatment. Histological analysis showed inflammatory infiltrate 14 days after treatment with ozonated oil and increased osteogenesis with Alveoliten ® management. Histomorphometric data were statistically analyzed by Kruskal–Wallis and Conover non parametric tests to establish differences between treatments. Findings revealed statistical differences between treatments after 7 ( p = 0.0010), 14 ( p = 0.0320) 21 days ( p = 0.0222). Ozonated oil induced initially a more intense inflammatory infiltrate but an osteogenic activity after 7 days. In conclusion Alveolar bone healing under dry socket condition presented better results when Alveotien ® was applied on this study.

Conflict of interest: This study did o not have any conflict of interest.

Only gold members can continue reading. Log In or Register to continue

Feb 5, 2018 | Posted by in Oral and Maxillofacial Surgery | Comments Off on Histomorfologic and histomorphometric study of bone healing in dry socket condition induced in rats treated with ozonized oil
Premium Wordpress Themes by UFO Themes