The population of the United Kingdom is becoming ever more obese, with similar findings demonstrated across the developed world. The incidence of oral and oropharyngeal cancer is also rising. Although…
Purpose: To present our experience with the management of 33 extensive mandibular ameloblastomas treated with segmental mandibulectomy, reconstruction with free fibula or iliac crest flap, and rehabilitation with immediate or…
Introduction: Regular over-ordering of cross-matched blood is expensive and can result in a shortage of available blood. In order to minimize the impact on an already over-stretched transfusion service, the…
Background and objectives: The ALT has become one of the first choices for reconstruction in defects involving the oral cavity and oropharynx. Or aim is to review the indications for…
Introduction: It is recognized that simulation can be used to aid the training of surgeons. Many courses give participants a certificate of completion rather than one of competence or proficiency….
Background and objectives: Reconstruction of jaw defects secondary to resections represents a surgical challenge. Mandibulectomy associated to soft tissues is usually required, bringing different degrees of esthetic and functional alterations….
Background: The benefits of induction chemotherapy in oral squamous cell carcinoma (OSCC) remain to be clearly defined, as trials to date have not shown a major survival benefit when induction…
Oral propranolol (PRN) has recently been shown to be highly effective for infantile hemangiomas (IHs), and is currently recommended as the first-line treatment of complicated IHs. However, no pharmacokinetic parameters…
Objective: To investigate the expression of Transient Receptor Potential Melastatin type 2 (TRPM2) in the human tongue squamous cell carcinoma tissues and SCC cell lines. The effect of activated and…
Purpose: To value the therapeutic effect of PUMA gene mediated by by radiation-inducible promoters in the treatment of Xenograft of human tongue squamous carcinoma in naked mice. Methods: Eukaryotic cell…
