U ulipristal ue-li-pris-tal (Ella) Do not confuse ulipristal with ursodiol. Category and Schedule Pregnancy Risk Category: X Drug Class: Contraceptive; progestin receptor modulator Mechanism of Action Postpones follicular rupture when administered prior to ovulation, thereby inhibiting or delaying ovulation. May also alter the normal endometrium, impairing implantation. Therapeutic Effect: Reduces chance of unintended pregnancy. Uses Emergency contraception following unprotected intercourse or possible contraceptive failure Pharmacokinetics Rapidly absorbed after oral administration. 94% plasma protein bound. Hepatic metabolism via CYP3A4 to active and inactive metabolites. Half-life: 32 hr. Indications and Dosages Emergency Contraception PO Adults (females). 1 tablet (30 mg) as soon as possible, but within 120 hr (5 days) of unprotected intercourse or contraceptive failure. Side Effects/Adverse Reactions Frequent Headache, abdominal pain, nausea Occasional Fatigue, dizziness Precautions and Contraindications Known or suspected pregnancy Drug Interactions of Concern to Dentistry • CYP3A4 inducers (e.g., carbamazepine, barbiturates, St. John’s wort): decreased effectiveness of ulipristal Serious Reactions ! None known Dental Considerations General: • Take precaution when seating and dismissing patient due to dizziness. • Increased risk of nausea and vomiting (e.g., during sedation and impressions). Teach Patient/Family to: • Inform dentist when drug has been taken. unoprostone isopropyl yoo-noh-prost′-ohn eye-seh-pro′-/> Only gold members can continue reading. Log In or Register to continue You may also need4: D19: T11: L7: G22: W18: S16: Q1: A Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Click to share on Google+ (Opens in new window) Related Tags: Mosbys Dental Drug Reference 11e Jan 5, 2015 | Posted by mrzezo in General Dentistry | Comments Off on 20: U
U ulipristal ue-li-pris-tal (Ella) Do not confuse ulipristal with ursodiol. Category and Schedule Pregnancy Risk Category: X Drug Class: Contraceptive; progestin receptor modulator Mechanism of Action Postpones follicular rupture when administered prior to ovulation, thereby inhibiting or delaying ovulation. May also alter the normal endometrium, impairing implantation. Therapeutic Effect: Reduces chance of unintended pregnancy. Uses Emergency contraception following unprotected intercourse or possible contraceptive failure Pharmacokinetics Rapidly absorbed after oral administration. 94% plasma protein bound. Hepatic metabolism via CYP3A4 to active and inactive metabolites. Half-life: 32 hr. Indications and Dosages Emergency Contraception PO Adults (females). 1 tablet (30 mg) as soon as possible, but within 120 hr (5 days) of unprotected intercourse or contraceptive failure. Side Effects/Adverse Reactions Frequent Headache, abdominal pain, nausea Occasional Fatigue, dizziness Precautions and Contraindications Known or suspected pregnancy Drug Interactions of Concern to Dentistry • CYP3A4 inducers (e.g., carbamazepine, barbiturates, St. John’s wort): decreased effectiveness of ulipristal Serious Reactions ! None known Dental Considerations General: • Take precaution when seating and dismissing patient due to dizziness. • Increased risk of nausea and vomiting (e.g., during sedation and impressions). Teach Patient/Family to: • Inform dentist when drug has been taken. unoprostone isopropyl yoo-noh-prost′-ohn eye-seh-pro′-/> Only gold members can continue reading. Log In or Register to continue You may also need4: D19: T11: L7: G22: W18: S16: Q1: A Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Click to share on Google+ (Opens in new window) Related
Emergency Contraception
