Background and objectives: This study describes the successful use of nasolabial flap or laser for the treatment of oral submucous fibrosis. To evaluate the efficacy of nasolabial flaps and lasers in the treatment of oral submucous fibrosis.

Methods: 20 healthy individuals were selected with oral submucous fibrosis (mouth opening from 0 to 25 mm). Exclusion criteria included compromised immune system, specific medical comorbidities. Patients were divided into 2 gorups: Group A: 10 patients were treated with lasers. Group B: 10 patients were treated with nasolabial flaps.

Results: In group A, mean increase of 15.2 mm was observed and 1 case of relapse was reported. In group B, mean increase of 22.4 mm was observed and no case of relapse was reported.

Conclusion: Laser excision is a more viable option for moderately affected cases (Grade III), while Nasolabial flap treatment is the treatment of choice for severely affected cases (Grade IV).

Key words: nasolabial flaps; lasers; OSMF