Objective: To explore the surgical treatments for skull base malignant neoplasms.

Methods: The study was conducted from January 2010 to January 2013. Totally 11 patients with skull base malignant neoplasms were treated by operation, including 8 in anterior skull base, 2 in lateral skull base and 1 in lateral-posterior skull base. The neoplasms were complete resected via different surgical approaches in all cases.

Results: All patients were followed up for 2 years, 2 of them died during the follow-up period, in which two patient with extensive neoplasm in lateral skull base died of tumor recurrence after six months postoperative.

Conclusions: The surgical treatment was the first treatment option for skull base malignant neoplasms. Besides the surgery, the site, range, pathology and adjuvant therapy of the skull base malignant neoplasms also had effect on the therapeutic results.

Key words: skull base neoplasm; surgical procedures; neurosurgery; maxillofacial surgery