Submandibular gland involvement in ssc
Aim: The aim of study was to investigate the involvement of the submandibular gland in patients with oral cavity squamous cell carcinoma oft the tongue and floor oft the mouth….
Association between gene polymorphisms with oral squamous cell carcinoma risk and survival in multiple ethnicities: a systematic review
Background: There are more than 30 genes polymorphisms associated with risk and survival rate of oral squamous cell carcinoma (OSCC). Nevertheless, different ethnicity could show different genotype and allele as…
Human papillomavirus related to head and neck squamous cell carcinoma
Squamous cells carcinoma (SCC) is a malignant neoplasm drift of the squamous epithelium and it’s characteristic is multifactorial etiopathogenesis. Nowadays it’s known that Human Papillomavirus (HPV) is a risk factor,…
A new treatment option for lichen planus – a pilot study
Lichen planus is a relatively common disorder, estimated to effect 0.5–2.0% of the general population. It is a chronic inflammatory disease affecting mucosal and cutanous tissue. Various treatment regimens have…
Gemcitabine induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer
Background and objectives: Gemcitabine (GEM) is a pyrimidine nucleoside analogue that is a new chemotherapeutic agent used for treating various cancers. Because accumulating evidence indicates that GEM may activate host…
Discrepancy between clinical and pathological staging of head and neck cancer – ‘the stage migration’
Rationale: The TNM system for classification of Head and neck malignant tumours is a universally accepted, widely used, staging method which helps clinicians and researchers to choose from treatment options,…
Outcome of head and neck cancer patients in palliative care
Introduction: In the UK 5000–7000 head and neck cancer cases are diagnosed annually. Only 50 per cent are curable. The remaining terminal cases are managed by palliative care services in…
Continued monitoring of salivary interleukin-6 levels may predict early and late locoregional recurrence in patients with oral squamous cell carcinoma
Background and objective: We have already demonstrated that post-operative concentration of salivary interleukin-6 (IL-6) may predict early locoregional recurrence in oral squamous cell carcinoma (OSCC) (Head & Neck; 2012). This…
Diagnostic value of mri in measurement of tumor thickness in tongue cancer: a comparative study according to tumor location
Background and objectives: The most important prognostic factor for survival in tongue cancer is the presence of cervical lymph node metastases. Their presence determines the therapeutic strategy. 20–30% of stages…
Oral squamous cell carcinoma of bangladeshi patients: a survival study
Introduction: In the oral cavity the most common malignant lesion is Squamous cell Carcinoma. Though the primary modality of treatment for patients with oral cavity cancer remains surgical resection, reconstruction…
Histologic evaluation of the effects of irradiation on mandibular bone in minipigs – preliminary results
Background: Radiation therapy is often part of treatment of head and neck malignancies. After radiotherapy patients are at risk to develop osteoradionecrosis. The development of osteoradionecrosis is unpredictable and has…
Diagnostic accuracy of ultrasound in distinguishing between inflammatory, benign and malignant pathology of the major salivary glands
Background and objectives: Patients with major salivary gland pathology may present with a suspected mass, diffuse glandular enlargement or symptoms of obstruction and inflammation. Various imaging modalities are available for…
Helicobacter pylori in patients with oral cancer
Helicobacter pylori is a microaerophilic bacteria, gram-negative, spiral shaped and mobile which is believed to be one of the main factors responsible for gastritis, gastric ulcers and gastric cancer. H…
Transoral robotic surgery with risk-adapted adjuvant therapy for oropharyngeal cancer
Introduction: Transoral robotic surgery (TORS) has been advocated as a means to de-intensify adjuvant therapy and to improve functional treatment outcomes in advanced stage oropharynx cancer. The purpose of this…
Prognostic factors for recurrence of oral cancer in northern spain
Background and objectives: Squamous cell carcinoma of the oral cavity is one of the ten most frequent cancers in developed countries. The purpose of this study was to identify predictors…
Diagnosis and treatment of floor of mouth carcinoma in japan
Objectives: The floor of mouth carcinoma (FOMC) displays some different characteristics compare to the other sites of oral squamous cell carcinoma (OSCC). This study aims to determine the characteristics and…
The antiapoptotic mechanism underlying drug resistance of oral squamous cell carcinoma
Background: Oral cancer, predominantly oral squamous cell carcinoma (OSCC) is the most common head and neck cancer. Despite advances in the treatment, the mortality rate of this disease has not…
Transcriptional factor ID-1 facilitates invasion and neoangiogenesis in head and neck squamous cell carcinoma
Squamous cell carcinoma is one of the most common malignancies in head and neck region. Primary tumors, especially derived from undifferentiated cells, tend to have an aggressive phenotype, mainly characterized…
Coordinated expression of keratin17 and 14-3-3 sigma regulates in cell proliferation and migration of oral squamous cell carcinoma
Background and objective: We have reported reciprocal switching in the keratin (K) subtype expression from K13 to K17 occurs during malignant transformation of the oral mucosa from normal and dysplastic…
Squamous cell carcinoma of the oral cavity in young patients: Vall D’Hebron hospital experience
Introduction: Squamous cell carcinoma of the oral cavity usually affects patients between the fifth and seventh decade of life but is increasingly seen in young patients under 40 years. Material…
