16.3
Pregnancy and Breastfeeding
Section I: Clinical Scenario and Dental Considerations
Clinical Scenario
A 24‐year‐old pregnant patient attends her routine dental check‐up complaining that her gums feel swollen, with associated sensitivity and bleeding when brushing her teeth.
Medical History
- Pregnant – 10 weeks at presentation
- Nausea/morning sickness since the fifth week
- Subclinical hypothyroidism
- Migraines
- History of vertebral fractures due to car accident (2 years earlier); episode of peripheral dizziness 4 weeks earlier attributed to residual cervical spine damage
Medications
- Folic acid
- Levothyroxine
- Potassium iodide
- Doxylamine/pyridoxine
Dental History
- Dental anxiety related to unpleasant experience as a child when a filling was placed without local anaesthesia
- Two years earlier, the patient underwent oral rehabilitation with fixed prosthesis with conscious sedation
- History of orthodontic treatment (from 10 to 16 years old)
- Wears an occlusal splint nocte
- Brushing teeth twice daily but has been using a soft brush as the gums feel sore
- Diet: consuming ginger ale regularly during the day to manage her nausea; unable to tolerate full meals; snacks on small amounts of food throughout the day
Social History
- Married
- Works as an accountant
- Travels to appointments using her own car
- Nil tobacco/alcohol consumption
Oral Examination
- Poor oral hygiene
- Swollen/inflamed gingivae which bleed easily on contact (Figure 16.3.1)
- Fully dentate
- Left temporomandibular joint click on opening
Structured Learning
- Apart from the poor oral hygiene, what could have caused the change in gingival appearance?
- Pregnancy gingivitis, also known as gingivitis gravidarum, may present in the first trimester of pregnancy
- This form of gingivitis results from increased levels of progesterone and oestrogen causing an exaggerated gingival inflammatory reaction to local irritants
- Pregnancy gingivitis, also known as gingivitis gravidarum, may present in the first trimester of pregnancy
- What factors are considered important in assessing the risk of managing this patient?
- Social
- Drives to appointments (not suitable if dental sedation is considered)
- Medical
- Still in the first trimester of pregnancy when elective dental treatment should be avoided
- There can be an increased tendency to nausea and sickness
- Selective drugs prescription
- Risk of peripheral dizziness when reclined in the dental chair (car accident sequela)
- Dental
- Using a soft toothbrush which is likely to be ineffective at removing oral deposits
- Gingival recession can occur if the gingival inflammation persists
- Vomiting related to pregnancy increases the risk of dental erosion
- Cariogenic dietary habits
- Potential for anaemia and related oral manifestations due to poor oral intake
- Dental anxiety may reduce compliance for treatment
- Only strictly necessary radiographs should be undertaken
- Social
- When is it most appropriate to schedule her dental appointments for periodontal treatment?
- The patient is taking an antiemetic (doxylamine/pyridoxine) because of her hyperemesis gravidarum; it is preferable to wait a few weeks to see if she progresses favourably once the second trimester of pregnancy is under way, particularly as she is also anxious about dental treatment
- Elective dental procedures are also usually safer in the second trimester
- Avoid scheduling the patient when she usually feels the most tired (generally early in the morning)
- Following oral hygiene advice, the patient returns for periodontal treatment when she is 14 weeks pregnant. In order to assess her level of anxiety, you ask her to complete a Modified Dental Anxiety Scale questionnaire (see Chapter 15.1). Her score is 20 which means that she is extremely anxious. She requests dental sedation. What sedation technique do you choose?
- Close liaison with the patient’s physician is required before providing sedation
- One option which the physician could assist with is diphenhydramine, although consideration would need to be given to the fact she is already taking doxylamine, an antihistamine with sedative activity
- Avoid benzodiazepines, since they are not recommended in pregnancy or hypothyroidism
- Nitrous oxide may be employed with strict restrictions and a hospital setting may be preferable (the sessions should not exceed 30 minutes, and the oxygen concentration should not be lower than 50%)
- What considerations are there regarding the patient’s position in the chair?
- Place the backrest of the chair in the semi‐reclined position to promote respiration and prevent gastro‐oesophageal reflux
- Remember the patient’s history of peripheral dizziness and vertebral fractures
- Supine hypotensive syndrome occurs starting in the second trimester
- What factors may increase the risk of bleeding as the result of the periodontal treatment?
- The interproximal papillae in pregnancy gingivitis are oedematous and bleed easily but this can be controlled with local measures
- Hypothyroidism can cause vascular endothelial disorders but not in its subclinical form
- Unfortunately, the patient subsequently presents with a periodontal abscess in relation to #14. What antibiotics should be avoided in pregnancy?
- Do not prescribe metronidazole in the first trimester of pregnancy
- Clarithromycin is contraindicated throughout pregnancy and during breastfeeding
- Quinolones and tetracyclines should also be avoided during pregnancy
General Dental Considerations
Oral Findings
- Pregnancy
- Gingivitis: due to an increase in capillary patency, gingivitis affects the marginal gum and interdental papilla and preferentially occurs in patients with pre‐existing gingivitis (Figure 16.3.2)
- Periodontal disease: pregnancy does not cause periodontal disease but can worsen it in patients with pre‐existing periodontitis
- Gingival hyperplasia and bleeding gums: result from an increase in capillary patency
- Pyogenic granuloma (gravidarum): due to an increase in angiogenesis caused by oestrogens, sometimes combined with local irritative factors; more common in the first pregnancy and in the first and second trimesters; usually resolves spontaneously following childbirth (Figure 16.3.3)
- Qualitative changes in the saliva: these changes decrease sodium and pH levels and increase potassium, protein and oestrogen levels
- Tooth mobility: due to changes in the lamina dura, which generally resolve spontaneously after childbirth
- Enamel erosion: the increase in gonadotropin levels causes morning sickness, especially during the first trimester
- Risk of caries: the saliva concentration of Streptococcus mutans