Dental crowding as a caries risk factor: A systematic review

Introduction

The association between dental crowding and dental caries has long been accepted because of increased food accumulation and plaque retention in areas of crowding. The aim of this review was to evaluate this potential causal relationship systematically.

Methods

Six electronic databases were accessed, supplemented by manual searching of the references of the relevant retrieved articles, peer-reviewed orthodontic journals, and gray literature. Search terms included caries , decay , crowding , and irregularity . Non-English articles were excluded from the review in the study-selection stage. Data extraction and evaluation of primary studies were performed independently by 2 reviewers.

Results

The initial search retrieved 6914 citations. However, only 18 articles met the inclusion criteria. The qualitative systematic review included 8 studies, with articles of low or moderate quality. No association between crowding and caries was reported in 4 studies, a significant negative correlation was found in 2 studies, 1 study showed a direct and significant relationship, and another study showed a positive association in the mandibular anterior region but an inverse correlation in the maxillary posterior region.

Conclusions

To date, there are no high-quality studies to resolve the possible association between dental crowding and caries; further high-quality longitudinal studies are needed to clarify this relationship.

The assumption that dental crowding is a risk factor for dental caries has long been made. Crowding disrupts normal proximal and occlusal dental contacts that provide proper embrasures, spillways, and self-cleansing. In turn, crowding leads to food accumulation and plaque retention. It is therefore intuitive that crowding will increase the incidence of dental caries. However, this belief has not always been supported by the literature.

Studies evaluating the relationship between crowding and dental caries have shown contradictory results. Some authors have reported a positive correlation between malocclusion and the incidence of caries. Contrary to these findings, other authors failed to identify an association between crowding or its severity and dental caries. Others have even reported a negative correlation between crowding and caries, with a lower incidence of decay in subjects with crowding.

Caries is a common oral disease, and its rehabilitation is a costly and time-consuming procedure. Strong evidence linking crowding and the development of dental caries would prioritize orthodontic treatment as a measure for caries prevention and improved oral health. If evidence were found to support this contention, dental health personnel—including general dental practitioners, pedodontists, and orthodontists—would assume a preventive role. Consequently, decision makers would be required to reevaluate orthodontic treatment needs of dental patients with crowding.

The aim of this systematic review was therefore to assess the relationship between dental crowding and the development of dental caries.

Material and methods

This systematic review was performed in accordance with guidelines recommended by the Meta-analysis of Observational Studies in Epidemiology Group. Study designs included were observational studies analyzing the association between crowding and caries. Participants (intervention and control groups) included subjects with no crowding or crowding of various degrees. Eligible studies were intended to evaluate caries as an outcome measure.

To identify all studies examining the relationship between crowding and the incidence of caries, the following electronic databases were searched with no restrictions: Cochrane Library (May 9, 2011), NLM Gateway (searches Pubmed and Medline, from 1950 to May 15, 2011), LILACS (from 1992 to May 20, 2011), Google Scholar (from 1993 to May 20, 2011), and ISI Web of Science (from 1945 to May 27, 2011). The search terms were the following.

  • Search 1: Dental AND (crowd* OR irregular* OR imbricat* OR “arch alignment” OR malalign * ).

  • Search 2: (crowd* OR irregular* OR imbricat* OR “arch alignment” OR malalign*) AND (caries OR demineraliz* OR decay).

  • Search 3: Search 1 OR search 2.

A manual search was performed of dental and orthodontic peer-reviewed journals ( Journal of Dental Research , from 1960 to May 2011; Community Dentistry and Oral Epidemiology , from 1973 to May 2011; American Journal of Orthodontics , from 1980 to June 1986; American Journal of Orthodontics and Dentofacial Orthopedics , from July 1986 to May 2011; Angle Orthodontist , from 1980 to May 2011; and European Journal of Orthodontics , from 1980 to May 2011. The references of these articles were evaluated for relevant citations. Authors of studies requiring further clarification were contacted.

The search and article selection were performed by 3 researchers (S.M.S., A.A.A., and H.S.H.). Data extraction sheets were created. The primary studies were assessed independently by 2 reviewers (H.S.H. and Y.A.M.). Inconsistencies arose just twice. The first was a disagreement among 2 of the 3 researchers on the decision to include 1 article; the third researcher suggested excluding this article. The second was to assess whether the conclusion of 1 article represented the results reported. This was resolved by referring to the data extraction sheets and discussing the point of controversy until agreement was reached.

The inclusion criteria were (1) human studies; (2) studies reporting on the prevalence or severity of dental crowding and dental caries, and assessing the association between them; (3) only studies including a comparator, a control group with no or minimal crowding, or a comparator of varying severity; and (4) studies with statistical analysis.

The exclusion criteria were (1) animal studies; (2) literature reviews, books, and articles of expert opinion; (3) studies reporting on the prevalence of crowding or dental caries or both without assessing their associations; (4) studies using a nonspecific index of outcome measurement for caries or crowding (eg, dental aesthetic index of orthodontic treatment need, or collective index of malocclusion); (5) studies evaluating white lesions; (6) subjects with systemic diseases or dental or craniofacial anomalies that could affect the susceptibility to caries; and (7) non-English articles.

Quality assessment of the 8 included articles was performed. Points were allocated for the following criteria: study type, blinding, adequate reporting, comparator (group with no or minimal crowding), validity and reliability of recording method and index used for measuring crowding and caries, effect of confounding factors, and coding of subjects. The maximum quality score for any article was 24. Articles were designated as having low, moderate, or high quality according to their scores (low, 1-8; moderate, 9-16; high, 17-24). A detailed quality assessment is given in Table I .

Table I
Quality assessment of included studies
Study Study type a Blinding b Adequate reporting c Comparator d Validity, reliability of caries recording method e Validity, reliability of crowding recording method f Error of measurement g Confounding factors h Subgrouping i Coding j Score/grade
Hixon et al 1 2 3 3 1 2 3 race, missing teeth, sex; NS 1 crowding 16/moderate
Roder and Arend 1 2 2 1 2 2 missing teeth, sex; NS 10/moderate
Katz 1 2 1 3 2 4 race, sex, missing teeth, baseline oral status 1 crowding 14/moderate
Addy et al 1 2 2 1 1 4 race, sex, missing teeth, baseline oral status; NS 11/moderate
Helm and Petersen 1 2 3 2 1 1 3 age, sex, missing teeth 13/moderate
Stahl and Grabowski 1 2 2 1 1 1 missing teeth 8/low
Staufer and Landmesser 1 3 3 1 2 1 crowding 3 age, missing teeth, baseline oral status 2 16/moderate
Alsoliman 1 2 2 1 1 1 caries 2 missing teeth, sex; NS 1 11/moderate

NS , Not significant.

a Longitudinal study: 2 points; cross-sectional study: 1 point (maximum 2 points).

b Blinding: 2 points.

c Adequate reporting on subject criteria, subject distribution, and methodology: 1 point for each factor (maximum 3 points).

d Control group of normal occlusion or minimal crowding (up to 2 mm): 2 points; control of different grades of crowding: 1 point (maximum 3 points).

e Radiographic assessment: 2 points; visual examination: 1 point (maximum 2 points).

f Quantitative index: 2 points; visual: 1 point (maximum 2 points).

g Error of measurement for caries detection and measurement of crowding: 1 point for each factor (maximum 2 points).

h Effect of confounding factors considered (age, race, sex, missing teeth, and baseline oral status): 1 point for each factor. When there was no sex-related difference between caries incidence, 1 point was given because no correction was needed. When confounding factors had no effect (NS): 1 point was given for each factor (maximum 5 points).

i Subgrouping subjects to compare the effect of age and severity of crowding: 1 point for each factor (maximum 2 points).

j Coding of subjects and variables: 1 point.

No meta-analysis was performed because of the heterogeneity of these studies, inadequate reporting of the study designs, and other limitations in the quality of the articles ( Table I ). Also, a wide range of indexes was used to measure crowding and the prevalence of caries ( Table II ).

Table II
Indexes of outcome measurement, results, and conclusions of the 8 studies
Study Indexes used to measure crowding and caries Results Conclusions
Hixon et al Crowding: visual assessment of anterior overlap and posterior teeth where contacts not at maximum convexity.
Caries: DFS index (all teeth).
  • 1.

    The maxillary posterior segment showed significantly more caries where the proximal surfaces were in satisfactory alignment than where they were considered irregular.

  • 2.

    Only in the mandibular anterior area was the incidence of carious surfaces higher for irregularly aligned teeth than for the satisfactory contacts.

  • 3.

    The subgroup with severe crowding had significantly more caries in all areas except the maxillary posterior segment, where no difference was found.

  • 1.

    Only in the mandibular anterior area did the teeth with irregular contacts show a tendency toward more proximal caries, and the maxillary irregular posterior segments were negatively associated with caries incidence.

Roder and Arend Crowding: anterior (measured in 0.8-mm increments) and posterior (measured by 0, no crowding; 1, at least 1 mm of vertical or horizontal displacement; 2, crowding that prevents normal occlusion in centric occlusion).
Caries: DMFS index (maxillary anterior teeth)
  • 1.

    High caries and crowding scores in the maxillary anterior segments was found in 14- and 16-year-old students.

  • 2.

    A direct and significant association between crowding and proximal caries scores in the maxillary anterior segment was evident.

  • 1.

    Direct and significant relation of crowding to proximal caries scores in the maxillary anterior segment.

Katz Crowding: MIM and MIV.
Caries: DMFS index (for maxillary anterior teeth).
  • 1.

    A difference of 16 decayed, filled, and missing surfaces between the top and bottom quartiles of subjects with UANTCRD.

  • 2.

    Inverse relationship: the greater the UANTCRD score in millimeters, the lower the DMFS score.

  • 1.

    Inverse relationship: the greater the irregularity score of the maxillary anterior region, the lower the caries score.

Addy et al Crowding: standardized technique for recording alignment of individual teeth index (for all teeth not including second and third molars).
Caries: DMS index (for paired contralateral teeth).
  • 1.

    Lower caries experience was found for the irregular teeth, but the difference did not reach significance.

  • 1.

    No significant differences in the incidence of dental caries between regular and irregular teeth.

Helm and Petersen Crowding: anterior section (incisors) and 2 lateral sections (canine and premolars) deviation of at least 2 mm in any section.
Caries: DMFS index (for all teeth except third molars).
  • 1.

    DFS scores were higher in the subjects with maxillary and mandibular anterior crowding but did not reach statistical significance.

  • 2.

    The total DMFS scores were slightly, but not significantly, lower in the subjects with crowding, but they had significantly more untreated caries in the maxilla.

  • 3.

    The DMFS scores were not higher in the crowded dental arches.

  • 4.

    Only crowding in the incisor segments was associated with somewhat higher DMFS scores.

  • 1.

    Space anomalies do not predispose to caries; consequently, increased risk of caries need not be included in considerations of the indication for orthodontic treatment.

Stahl and Grabowski Crowding: any tooth rotated or out of line for which space would have to be created to allow correction of malalignment.
Caries: DMFT index.
  • 1.

    No significant difference was observed between the prevalence of malocclusion in caries-free and carious mixed dentition.

  • 2.

    Subjects with crowding in the posterior segments had significantly higher mean dmft scores compared with children with normal occlusion in the mixed dentition.

  • 3.

    Although high percentages of children with increased caries risk had crowding (17%), no positive correlation could be established.

  • 1.

    Statistically significant parallelism in prevalence of malocclusion and caries was found for posterior crossbite and mandibular overjet in children with mixed dentition.

Staufer and Landmesser Crowding: modified Lundström index (for mandibular anterior teeth).
Caries: DMF index (for mandibular anterior teeth).
  • 1.

    Crowding showed a nonparametric distribution. No sex-specific difference for the degree of crowding. No significant association between crowding and prevalence of caries.

  • 2.

    Age-specific difference in the degree of crowding, with the older group showing a higher prevalence.

  • 3.

    Prevalence values of caries were 39% in the older group and 19% in the younger group.

  • 1.

    No statistically secured correlation between abrasions or caries and the degree of crowding was recorded.

  • 2.

    The incidence of caries was twice as high in the older patients than in the younger patients.

Alsoliman Crowding: any tooth rotated or out of line for which space would have to be created to allow correction of malalignment.
Caries: dmft index.
  • 1.

    Crowding was found significantly most often in caries-free dentitions.

  • 2.

    Crowding was correlated negatively with caries experience with significantly greater dmft values in uncrowded subjects than in crowded subjects.

  • 1.

    Crowding and caries were negatively correlated with significantly greater dmft values in subjects with no crowding.

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Apr 8, 2017 | Posted by in Orthodontics | Comments Off on Dental crowding as a caries risk factor: A systematic review
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