Objective: Matrilin-3, a structural protein of the cartilage extracellular matrix, has a role on chondrocyte proliferation. Gene alterations of matrilin-3 may cause skeletal and chondro-cartilage diseases like Temporomandibular joint internal…
Osteochondroma is rare in the craniofacial skeleton and in particular in the mandibular condyle. The debate continues as to whether the osteochondroma represents a true neoplasm or is a hyperplastic…
Effect of ice compression on pain after mandibular third molar surgery: a single blind randomized controlled trial Introduction: The aim of this study was to investigate the effect of compression…
Habitual TMJ luxation is a rare but serious condition for the patient, and is often managed by extensive open joint surgery. Arthroscopic eminoplasty is described as alternative to open eminoplasty,…
A variety of grafting materials, joint prosthesis and the treatments used in the total reconstruction of the TMJ are many and are often contradictions regarding its indications and applications, yet…
An internal derangement occurs when there is disturbance in the normal anatomic relationship between the disc and condyle of the Temporomandibular Joint (TMJ) that interferes with smooth movement of the…
This case presentation refers to a 56 year old male patient, which is diagnosed with a recurrent keratocystic odontogenic tumor that completely compromises the left ascending ramous, condylar complex and…
Authors performed a prospective study in 100 patients with chronic anterior disc displacement without reduction. Patients with subjective problems lasting less than one year were assigned as group A (…
TMJ Osteoarthritis (OA) is defined as a chronic and degenerative disease with an important yet secondary inflammatory component and is the result of an unbalance anabolic and catabolic metabolism inside…
Background and aim of study: To evaluate the effect of primary diagnostic arthroscopic procedures on TMJ Synovitis when compared to secondary surgical arthroscopic findings and its impact on the final…
Introduction: Bisphosphonates have been therapeutically used for the management of lytic bone diseases. Their use has been increased nowadays and besides that associated adverse effects have been amplified. Jaw osteonecrosis…
Patients that have undergone to total TMJ prosthetic reconstruction for different reasons, such as trauma, degenerative diseases and cysts. TMJ total prosthetic reconstruction turned up to be a wonderful manner…
To apply human embryonic stem cells (hESCs) as a source of osteoblast-like cells (hESC-OS), factors influencing bone formation potential of hESC-OS need to be evaluated. Aims: The study aimed to…
Objectives: Mesenchymal stem cells (MSCs) isolated from various tissues have been used for clinical application in tissue engineering and regenerative medicine. To date, the most common source of MSCs has…
Introduction: Periodontitis is the most common cause for tooth loss in adults and advanced types affect 10–15% of adults worldwide. The attempts to save tooth and regenerate periodontal apparatus including…
Stem cell therapy for tissue guided bone regeneration is a promising approach and widely studied in maxillofacial surgery i.e. bone regeneration and implant surgery. Aim: The concept using mesenchymal stem…
Aim/objective/purpose: To present a novel guided bone regeneration (GBR) concept that consists of combining Boneject ® (a biomaterial containing atelocollagen and bovine hydroxyapatite particles) with thermoplastic, bioresorbable plates (DeltaSystem ®…
Objectives: The efficacy of rhBMP2 with bone grafts (rhBMP2-BG) in promoting adequate bone formation within critical size defects is documented. However, the efficacy in treating jaw resection (including segmental) has…
Purpose: To analyze effect of an alternating distraction–compression protocol over conventional distraction osteogenesis (DO) protocol on new bone formation. Materials and methods: Eighteen rabbits underwent bilateral mandibular corticostomy, custom-made distractor…
Aseptic osteolysis is a main cause of loosening of orthopaedic implant failures. The wear debris derived from polymers (UHWMPE) and/or metals of implants (Ti) elicit primary inflammatory and secondary osteolytic…
