Aims: The objective of this study is to evaluate the different applications of botulinum toxin-A in functional pathologies of maxillofacial territory.

Methods: In this prospective study, thirty-three participants that required botulinum toxin-A treatment, were received in the maxillofacial surgery service of the Hospital Clínico Mutual de Seguridad in a period of three years.

Botulinum toxin-A was infiltrated to patients with the following medical diagnosis: oromandibular post-trauma dystonia, unilateral hypertrophy of the masseter muscles, sialorrhea in neurological compromised patients and bruxism.

The same protocol was used in the infiltration of masticatory muscles or salival glands in all the patients, depending on their pathology. Patients were followed for the mean of one year and six months. The obtained data was registered in tables and questionnaires in each control. The data were statistically analyzed. The present study was accepted by the Ethical Committee of the current Hospital.

Results: The results are presented as Graphics and tables. The analysis of all the variables demonstrated that there was an improvement of signs and symptoms in every evaluated criteria. No complications were registered.

Conclusions: The infiltration of botulinum toxin-A with this protocol achieves an improvement in every studied pathology. We recommend the utilization of this protocol with minimum possibility of complications.

Conflict of interest: None declared.