We have proposed our original guidelines for management of patients receiving bisphosphonates (BPs) in 2008, and have managed 666 patients according to our guidelines till February 2013. Patients were classified…
Background and objectives : Since the first description of bisphosphonates related osteonecrosis of the jaw (BRONJ) made in 2003 there has been an increased number of cases described in the…
Background and objectives : Treatment of bisphosphonate (BP)-induced osteonecrosis of the jaws (ONJ) varies from conservative to surgical and there exist no global consensus. Since 2010 we have used a…
Background : Bisphosphonate-related osteonecrosis of the jaw has become a well known problem of rising clinical importance. The treatment is exceptionally hard. Fluorescence guided bone resection is a promising technique…
Background and objetives : Bisphosphonates are antiresorptive drug fully accepted for the treatment of metastatic bone disease, osteoporosis and other bone diseases. In 2003, Marx published 36 patients with exposed…
Background : Osteonecrosis of the jaw occurs in patients receiving high doses of intravenous nitrogen-containing bisphosphonates in the course of their supportive cancer therapy. The exact pathomechanisms are elusive and…
Treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ) remains an intractable problem in many cases. Recent literatures have shown that the new treatment modality using teriparatide may be beneficial to…
Background and objects : The radiographic criteria of bisphosphonate-related osteonecrosis of the jaws (BRONJ) have only been investigated in few studies yet. All of them comprised just limited cohorts. It…
Objectives : To evaluate functional condition of the inferior alveolar nerve in acute odontogenic inflammatory processes of mandible by means of the stimulative electroneuromyography. Methods : Sixty patients with acute…
Background : Bone biomarkers have been suggested for the risk assessment for osteonecrosis of the jaw, a serious complication associated with bisphosphonate (BP) use; however, no consensus has been reached….
Bisphosphonates are drugs used in treatment of different pathological conditions that affect bones, such as osteoporosis, metastatic bone disease, Paget disease and osteogenesis imperfecta, etc. The aim of the study…
Background and objectives : Bisphosphonates (BIS) has a beneficial effect in patients whosuffer from osteoporosis and bone metastasis, however, adverse consequences such as osteonecrosis of the jawmayoccur. Our aim was…
Bisphosphonate Related Osteonecrosis of the Jaw (BRONJ) is a severe complication described as an area of bone in the jaw that has necrosed and been exposed in the mouth for…
Background and objectives : BRONJ is characterized by a chronic soft tissue wound and bone necrosis exclusive to the jaws of a fraction of patients taking bishosphonates. Oral bishosphonates are…
Background and objectives : Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an important complication in cancer patients taking intravenous Bisphosphonates. In most cases, BRONJ is associated with an oral surgery…
Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) simulates tissue regeneration and can be usefull in treating osteonecrosis bisphosphonate induced. Material and methods : Between January 2012 and January…
Introduction : ONJ risk factors include the exposure to the long term doses of intra-venous bisphosphonates, concomitant use of corticosteroids (combined therapy) and a surgical dental procedure. The aim of…
The frequency of BRONJ following dental extraction in osteoporotic patients on oral bisphosphonates is of key interest to Oral and Maxillofacial Surgeons. The estimated frequency of the pathology ranges from…
Osteonecrosis of the jaw has been increasingly suspected to be a potencial complication of biphosphonate terapy in the recent year. These drugs are used in the cronic treatment of osteopenic…
Abstract The present study evaluated the use of this self-activated shape memory alloy (SMA) device, with a focus on its effects in the region under the periosteum. Materials and methods…
