The frequency of BRONJ following dental extraction in osteoporotic patients on oral bisphosphonates is of key interest to Oral and Maxillofacial Surgeons. The estimated frequency of the pathology ranges from 1 in 251, to 1 in 296 to 11302, and 1 in 952 to 15373. There is also estimated figure of 1:10000 to 100,000 suggested by the American Bone and Mineral Research Group. 4900 consecutive patients on oral bisphosphonate for osteoporosis were included in the study over a 6 years period. Detailed demographic information was recorded. There were 4 cases of BRONJ. All the affected individuals were elderly, medically compromised and were on Alendronate. The overall frequency of BRONJ was 1 in 225.
The frequency of bisphosphonate related osteonecrosis of the jaws (BRONJ): a single centre prospective
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