Papillon-Lefevre syndrome • Periodontal disease associated with Papillon-Lefevre syndrome (PLS) affects the primary and permanent dentition. • Keratosis of the palms and soles and the dorsal surfaces and other skin…
Key points • Chromosomal aneuploidies are caused by nondisjunction of chromosomes in meiosis or mitosis. • Down syndrome is caused by trisomy of chromosome 21. • Klinefelter and Turner syndromes…
Cornelia de Lange syndrome • Syndrome is a clinical diagnosis. • Many craniofacial abnormalities include synophrys, long philtrum, and cleft palate. • Limb malformations are seen in these patients, along…
Key points • Many syndromes affecting the central nervous system (CNS) demonstrate both intraoral signs as well as head and neck manifestations. • Their causes include, but are not limited…
Key points • Hamartomas are benign malformations presenting as an excess of normal tissue within the tissue of origin. • Although some syndromes show a clear genetic transmission, the underlying…
Key points • There are over 500 syndromes with clefting as part of the phenotype. • An understanding of sequence is needed to effectively manage patients with clefting disorders. •…
Key points • Branchial arch syndromes present with variable expressivity. • Management necessitates a multidisciplinary approach. • Features corroborate a disorder with first and second branchial arch derivatives. • Treatment…
Key points • Ehlers-Danlos syndromes are a heterogeneous group of disorders characterized by abnormal formation of collagen or molecules related to collagen synthesis, abnormalities in the matrix glycoprotein tenascin, and…
Key points • Genetic alterations can cause physiologic responses resulting in systemic and metabolic complications. • These complications can cause significant deficits, as in Hurler and Williams syndromes, which can…
Key points • Look beyond the primary jaw pathology for clues of syndromic involvement. Observe the skin, and always consider extrafacial skeletal involvement. • Study Gorlin’s Syndromes of the Head…
Key points • Craniosynostosis syndromes have wide phenotypic variability. Understanding of the underlying genetic causes continues to develop. • Children with these syndromes are best managed at a multidisciplinary craniofacial…
Dean M. DeLuke, DDS, MBA, Editor The purpose of this issue of the Atlas of the Oral and Maxillofacial Surgery Clinics of North America is to serve as an aid…
To: Dr. Dominick J. DeLuke and Dr. Leon Eisenbud. In recognition of their many contributions to the profession, and with thanks for allowing me to “see a little further by…
Forthcoming Issues March 2015 Diagnosis and Management of Neck Masses David E. Webb, Editor September 2015 Adjuncts for Care of the Surgical Patient Sidney Bourgeois, Editor Previous Issues March 2014…
Consulting Editor RICHARD H. HAUG, DDS Professor and Chief, Oral and Maxillofacial Surgery, Carolinas Center for Oral Health, Charlotte, North Carolina Editor DEAN M. DeLUKE, DDS, MBA Associate Professor and…
