BONJ is an iatrogenic illness described in 2003. In those 10 years, therapeutic attitude has changed from more conservative to more invasive.

The aim of this study is to demonstrate that surgical treatment in specific cases can improve or even heal BONJ injuries.

Forty-nine patients were diagnosed, treated and followed-up in our hospital. Depending on clinical and radiology features, patients were treated with antibiotherapy or surgical treatment plus antibiotherapy.

Surgical treatment was performed with extensive approach, deep curettage and hermetic closure when possible.

The protocol allowed us to achieve good results in our patients, shown in the study.

Key words: osteonecrosis; bisphosphonates; jaw