Dental infection can be localized in the oral cavity or produce remote infection by hematogenous dissemination of microorganisms or their antigenic components.

Method used/case report: We report five cases in children aged 6–12 years with dental infection that undertook various tissues such as mediastinum, brain, blood vessels, eyeball and femur.

Results: Two of the five patients had osteomyelitis of the mandible of dental origin that led to osteomyelitis in the femur and orbital abscess. One patient presented Mediastinitis from hidden cavities. Another, chronic infection of lower teeth presented Henoch–Shönlein vasculitis and the fifth after extraction of the upper incisor, cerebritis.

Five patients underwent surgical medical management.

The most frequently performed treatment consisted of: tooth extractions, sequestrectomy and decortication.

It was followed by clinical and imaging (CT and panoramic Rx) for 6 months.

The patients showed a favorable evolution after the cause was removed. Only in the vasculitis of Henoch–Shönlein reoperation was required on two occasions and analgesic therapy for a month with a year improvement.

Among the effects that patients had the most frequent was the loss of teeth and bone.

Conclusions :

• 1.

  Dental infection generated different infections in other organs and tissues.

• 2.

  The chronic nature of dental infection stimulates the distant immune response.

Conflict of interest: None declared.