Objective: To present three cases of adolescent patients with Crouzon syndrome treated with a protocol for diagnosis and surgical orthodontic treatment – psychological, obtaining stable results over time and working in interdisciplinary teams.

Patients and methods: In the first patient, a woman of 16, with Crouzon syndrome, moderate hypoplasia of the midface, exoltalmos moderate, severe malocclusion, Class III.

We used a diagnostic protocol based on clinical examination, cephalometric, with models mounted in articulator in CR.

The treatment plan was based on functional and aesthetic objectives, outlined in an orthodontic-surgical VTO, timed.

The surgical techniques used were conventional osteotomies, midface advancement, 9 mm in one time, with autologous bone grafts and titanium rigid fixation.

In the second case, male patient aged 22 with Crouzon syndrome, exoltalmos moderate, Class III skeletal and dental.

Technique was used extraoral distraction osteogenesis, RED I, for the advancement of 23 mm of midface.

The third patient: cleft lip and palate, severe maxillary hypoplasia, has been treated with distraction osteogenesis advancement, through Le Fort I osteotomy.

Results: Using a good protocol timing of diagnosis and treatment, we obtained the functional and aesthetic objectives desired by patients and the interdisciplinary team treating and most importantly the results are maintained over time.

Conclusion: In patients with craniofacial anomalies, successful results can be achieved by following a protocol for working with functional and aesthetic objectives very clear.

Correctly applied and modern surgical orthodontic resources available according to the needs of each case.

Conflict of interest: None declared.