Odontogenic myxoma: clinicopathological findings in a Nigerian tertiary hospital

Introduction: Odontogenic myxoma is a rare benign neoplasm of controversial origin. It has been reported to account for varying percentages of odontogenic tumours. Some authors have documented it as a rather aggressive tumour with a relatively high recurrence rate. This study aims to describe the pattern, immunohistochemical findings and outcome of management in a Nigerian tertiary hospital.

Materials and methods: The medical records of patients with histologically diagnosed odontogenic myxoma between 1990 and 2010 were extracted from a pool of odontogenic tumours. Information on biodata, duration, site, radiological appearance of tumour, treatment undertaken and the presence/absence of recurrence was documented. Immunohistochemical findings on some of the tumours were also described.

Results: Data was complete on 23 cases of odontogenic myxoma and were therefore included in the study. The mean age of the patients was 31.96 years and the mean duration of lesion before presentation was two years. The odontogenic myxomas were commoner in the mandible and 17.4% were peripherally located. Majority of the patients had segmental jaw resections. No recurrence was recorded in the follow up period. The immunohistochemical findings showed no reactivity for AE1/AE3 and Epithelial Membrane Antigen.

Conclusion: Odontogenic myxoma remains a tumour of questionable origin and varied radiological appearance. Poor patient follow in our environment precludes adequate assessment of patients following treatment.

Conflict of interest: None declared.

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Feb 5, 2018 | Posted by in Oral and Maxillofacial Surgery | Comments Off on Odontogenic myxoma: clinicopathological findings in a Nigerian tertiary hospital
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