The use of osteointegrated implants to rehabilitate large bone defects is still a challenge for surgeons. This is a good option of anchorage to provide support for a maxillary-dental-facial prosthesis in other bones of the face. The aim of this work is to present a case of a 55 years old male patient that presented a cancer in the region of the right maxillary sinus and was submitted to maxillectomy and radiotherapy describing the important of a multidisciplinary approach of the treatment. The patient used a removable partial denture for 5 years but it had no retention or stability. Thus, it was suggested the use of dental implants to anchor a new removable denture. The procedure was done under general anesthesia, the implants were placed in the right side on the residual zygomatic bone, infraorbital ridge and on the left side the implants were placed in the region of the alveolar ridge. After six months, implants were exposed and transferred to manufacturing the trans palate metal infrastructure. Subsequently a new denture with clips of retention was done. Two years after this, the patient was submitted to skin graft to reconstruct face in the area of the tumor. Today, the patient is in a 6 months of follow-up, pleased with the result. When professionals from different areas work together it is possible to rehabilitate large bone defects having good results both clinically and psychologically to the patient.

Conflict of interest: None declared.