Salivary lithiasis is defined as the obstruction to the salivary outflow due to a calcaric stone (sialolithe) located through the excretory system of the gland. It is the most common pathology of the salivary glands (30%) and affects up to the 1.2% of the adult population.

It can affect any gland, but most often involves the submandibular gland (80–94%) followed by the parotid gland (4–20%). Its clinical presentation is variable, being in some cases of sudden onset and acute, along with marked glandular swelling of the affected territory, pain, decreased salivary flow and infection, while in others the symptoms are more chronic, with a diffuse discomfort with permanent glandular induration.

It is important to make a correct initial diagnosis and subsequent differential diagnosis of systemic diseases that occur with the presence of glandular stones, in order to implement the most appropriate treatment for each case.

We present two cases of massive bilateral microlithiasis of parotid gland, that cursed with chronic and latent symptoms and were diagnosed by imaging test. We describe the clinical and diagnostic information of each patient and the therapeutic options according to the literature review.

Conflict of interest: None declared.