Inflammatory pseudotumour (IPT), also known as inflammatory myofibroblastic tumour (IMT), plasma cell granuloma, plasma cell pseudotumour and pseudosarcomatous tumour, is a benign but locally aggressive tumour which may behave in malignant fashion. It is composed of variable admixture of inflammatory cells and myofibroblasts, one component of which may predominate almost to the exclusion of the other. IMT with added myofibroblasts has been described as a discrete entity. IgG4-related immunopathologic process is linked to the pathogenesis of IPT. Chromosomal rearrangement of anaplastic lymphoma kinase (ALK) gene is seen in a proportion of cases and this is considered to be neoplastic.

The clinical presentation and behaviour are unpredictable. Management includes surgery, steroid or radiotherapy, or a combination of the three. Many sites may be affected, but the lung is the commonest. In the head and neck, IPT of the orbit, larynx, oropharynx, paranasal sinuses and tongue have been reported, including approximately 20 cases in the maxillary sinus. R uaux et al. believe sinonasal IPT to be distinct from those from other sites in terms of clinical behaviour, radiological features and in the response to treatment.

We present a case series of three interesting cases of maxillary (sinonasal) IPT/IMT.

Conflict of interest: None declared.