In 2003 began to be published the first cases of osteonecrosis of the jaws associated with the administration of intravenous bisphosphonates. The aim of our contribution is to present a case of bisphosphonate osteonecrosis over time rehabilitated with very good result by an implant supported prothesis.

Materials and methods : We report the case of a 67 years old man, with a clinical history of multiple myeloma treated with zoledronic acid, referred to our clinic for an evaluation of a suspected bisphosphonate osteonecrosis ulcerative lesion on maxillary gingiva. After making extractions and curettage, pathologic examination confirmed the diagnosis. Because of the good clinical outcome, after 23 months, we decided the placement of two zygomatic, one pterygoid and one short dental implant in premaxilla.

Results : Five months after the implant placement, we performed splinting and placement of definitive implant prosthetics. Evolution has shown an excellent implant osseointegration, support and stability of the prothesis. Quite there are so many reported cases of bisphosphonate osteonecrosis after treatment with dental implants, there are not already cases of successfully implant rehabilitated patients after the disease.

Conclusions : Control of bisphosphonate osteonecrosis after prolonged follow-up, should not prevent making a satisfactory implant rehabilitation.

Key words : osteonecrosis; bisphosphonates; implants