HSY cells and HSG cells, but not HSC-2 cells and HaCaT cells, exhibited palmitate-induced cell shape change and lipid accumulation. A representative image (×400) of cells treated with control (BSA) or palmitate (500 μM) for 24 h. Arrow heads indicate cytoplasmic lipid droplets. Scale bars = 20 μm
In conclusion, our data indicate that palmitate may exacerbate the pathogenesis of primary SS. Results presented in this report should encourage further investigations on relationship between metabolic-related disorders and autoimmune diseases such as primary SS.
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