Keratocyst Odontogenic Tumor (KCOT) is a benign intraosseus neoplasm that occurs between the second and third decade of life. The main location is the third molar and angle region of the mandible and could extend towards the ramus or body. Its importance lies in the high rate recurrence, understanding histological variants allow predict prognosis and tumor aggressiveness. To reduce the high recurrence rate of KCOT, it is essential to eradicate the epithelial component of the cyst completely, occasional association with basal cell nevus syndrome. However, radical treatment is associated with numerous complications, including facial deformity, missing teeth, infection of transplanted bone, and permanent numbness of the region innervated by the mental nerve when OKC involves the inferior alveolar nerve. Among the surgical conservative treatments include marzupialization or decompression, but according to the literature does not rule out the possibility of more aggressive treatments such as partial or total removal of the mandible.

We report a case of 59 years old female patient, who present a growing overinfected intraosseus right mandibular KCOT. She was treated by marzupializion. Further, the decreased tumor was completely removed. No recurrence and new bone formation was observed in 1 year.

Conflict of interest: Conservative treatment of extensive KOCT by marzupialization.