Common Abbreviations Utilized in Prescription Writing
There are many variations of abbreviations in writing prescriptions. One must be very cautious in using them. A few common ones to dentistry are listed in the table:
Abbreviation
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Its meaning:
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b.i.d. or b.d.
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Means twice daily
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npo
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Nothing by mouth
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po
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By mouth
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prn
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As needed
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q.6.h
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Every 6 h, you can change the number of hours, i.e., q.8.h means every 8 h
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stat
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Immediately
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t.i.d.
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Three times daily
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22.2 Antibiotics Indications
22.2.1 Precautions for All Antibiotics
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Note that all antibiotics have the potential to interfere with oral contraceptives. Patients should be advised to take additional precautions when taking antibiotics and oral contraceptives together.
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Antibiotics can cause “nuisance” diarrhea which is nonthreatening. Patient should call the prescriber before discontinuing the medication.
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In general all antibiotics have the potential of causing pseudomembranous colitis which manifests itself as severe diarrhea. The patient should be instructed to discontinue use of medication and seek treatment from their physician.
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In dentistry, antibiotic use should be limited to 7–10 days. Patients should be encouraged to seek treatment for their dental problems or return if their symptoms persist. Short term use of antibiotics will also prevent superinfections with fungal growth.
22.2.1.1 Guidelines for Antibiotic Prophylaxis
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For current guidelines on antibiotic prophylaxis for prevention of infective endocarditis, visit the American Dental Association(ADA) and the American Heart Association website at: http://www.ada.org/en/member-center/oral-health-topics/antibiotic-prophylaxis and http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/TheImpactofCongenitalHeartDefects/Infective-Endocarditis_UCM_307108_Article.jsp#.Vmrz1LgrK7Q.Cardiac Conditions for Which Prophylaxis with Antibiotics for Dental Procedures Is Recommended (AHA Guidelines Published May 2007):
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Prosthetic heart valve
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Previous infective endocarditis
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Congenital heart disease (CHD)
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Unrepaired cyanotic CHD, including palliative shunts and conduits
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Completely repaired congenital heart defect with prosthetic material or device whether placed by surgery or by catheter intervention, during the first 6 months after the procedure (endothelialization occurs within 6 months of procedure)
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Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or adjacent or prosthetic device (which inhibits endothelialization)
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Cardiac transplant recipients who develop cardiac valvulopathy
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Patients with any of the above conditions who are scheduled to undergo a dental procedure that is at risk of bleeding should be given antibiotics prior to initiation of procedures.
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For current guidelines on antibiotic prophylaxis in patients with prosthetic joints who may be at risk of developing infections following dental procedures, the ADA is a good site as well or the American Association of Orthopedic Surgeons Guidelines.ADA 2014 Clinical Recommendation
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In general, for patients with prosthetic joint implants, prophylactic antibiotics are not recommended prior to dental procedures to prevent prosthetic joint infection. For patients with a history of complications associated with their joint replacement surgery who are undergoing dental procedures that include gingival manipulation or mucosal incision, prophylactic antibiotics should only be considered after consultation with the patient and orthopedic surgeon. To assess a patient’s medical status, a complete health history is always recommended when making final decisions regarding the need for antibiotic prophylaxis.
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The most recent evidence-based guideline was published in the Journal of the American Dental Association (JADA) in 2015. This is accessible on: http://jada.ada.org/article/S0002-8177(14)00019-1/fulltext?nav=rotatorJanmain.
Antibiotic indication
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First choice: non-penicillin-allergic patients
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Second choice: penicillin-allergic patients
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Patients unable to take oral medication
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Prophylaxis for patients at risk for developing bacterial endocarditis
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aAmoxicillin 500 mg tabs
Disp: dependent on the anticipated number of appointments
Sig: Take 4 tabs (2 g) an hour before dental procedure
Also available in suspensions
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bClindamycin
150 mg tabs
Disp: dependent on the anticipated number of appointments
Sig: Take 4 (150 mg) tabs = 600 mgs; 1 h before dental procedure
Also available in suspensions
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Ampicillin 2 g IM or IV
For penicillin or ampicillin-allergic patients: clindamycin (600 mg IM or IV; 1 h before dental procedure)
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Prophylaxis for patients at risk for developing bacteremia in prosthetic joints
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Amoxicillin 500 mg tabs
Dispense 12 tabs
Sig: Take 4 tabs(2 g) 1 h before procedure
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Clindamycin 150 mg tabs
Dispense 12 tabs
Sig: Take 4 tablets = 600 mg an hour before procedure
Note: AAOS has no official recommendation for penicillin-allergic patients, this would be a reasonable alternative
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Acute dental infections where organism is unknown
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aPenicillin VK 500 mg tabs
Disp: 21 (twenty-one) tabs
Sig: Take 1 g = 2 tablets stat; followed by 500 mg q.6.h for 7 days
bClindamycin can also be considered depending on the severity of the infection or if no response is obtained after use of penicillin for 48 h
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bClindamycin 150 mg tabs
Disp: 21(twenty-one) tabs
Sig: Take 2 tabs = 300 mg stat; 1 tab q.6.h for 7 days
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Referral to emergency room for IV antibiotics
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Augmentin
500 mg (500 mg amoxicillin, 125 mg clavulanic acid)
Dispense: 21 (twenty-one) tabs
Sig. 1 tab po q.8. h until gone
Note
Augmentin is another option for non-penicillin-allergic patients; presence of clavulanic acid allows medication to be taken with or without meals.
22.2.1.2 Antibiotics for Upper Respiratory Tract Infections
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In patients with sinus congestion, a use of the over-the-counter decongestants would be helpful in conjunction with antibiotic use.
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Azithromycin (Zithromax) 250 mg tabs
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Dispense 6 tabs
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Sig: 2 tabs (500 mg) po on day 1; followed by 1 tab daily on days 2–5
Z-Pak-
Dispense: one
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Sig: Take as directed
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Contraindications: Allergy to erythromycin, high dose of theophylline, taking (Claritin) loratadine or astemizole, taking cisapride (Propulsid); liver disease
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