Angioneurotic edema is an acute swelling involving the submucosal or subcutaneous tissues, being most often located in the oral and maxillofacial region, which can result in upper airway obstruction. Its etiology is frequently associated with immunoglobulin-mediated hypersensitivity reactions that elicit a heightened inflammatory response. The objective of this study was to report the case of a patient who developed an episode of angioneurotic edema following combined orthognathic surgery. Pharmacological and nonpharmacological interventions used in the treatment of this important clinical condition are described and discussed.

Conflict of interest: None declared.