BFP is special source of tissue for oral defect because of its location, rich vascularization and stem cells. Surgical anatomy and various applications of BFP flap for reconstruction of soft and hard tissue defects will discuss here. Some common applications of BFP flap, like closure of oro-antral and oro-nasal communications and Repair of cleft palate especially in second approach in failed ones and Covering of regional pathologic soft tissue defect such as oral sub mucous fibrosis or traumatic mucosal defects or regional pathologic bone tissue defect such as exposed bone or osteoradionecrosis lesions and as a biologic membrane for coverage and bone in case of bone augmentation in posterior alveolar ridge and Repair of large perforation of Schneiderian membrane in sinus lifting for simultaneous implant placement and also in TMJ reconstructions. Also, the BFP could be removed by lipectomy to improve aesthetic by midfacial cheek hollowing and it also can be used for coverage of nerve repair and to reduce strength of postoperative scar and producing adipose drive stem cell for tissue engineering. Surgical access to BFP via posterior maxillary vestibule and upper anterior mandibular ramus and anatomic considerations like endangered nerve and vessels are also discuss in detail.