Aneurysmal bone cyst (ABC) is an expansive osteolytic lesion composed of variable sized spaces filled with blood, and it is considered a type of giant cell lesion. The prevalence is 1.4 per 100,000 individuals, representing about 1% of bone tumors. It can occur at any age but they are more common in patients younger than 20 years, approximately 10% are located in the head and neck region.

Clinical features includes localized pain, fast growing swelling and also in some cases inferior alveolar nerve paresthesia. The recurrence rate is approximately 30% and the prognosis is favorable.

The literature describes several protocols such as curettage, block resection with reconstruction, and therapeutic embolization for the treatment of ABCs.

We present three cases of large mandibular ABC, analyzing the selection of the treatment determined by the size of the lesion and its biological behavior.

Conflict of interest: None declared.