Overview and topographic anatomy
General information
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The pterygopalatine fossa is a pyramid-shaped fossa on the lateral aspect of the skull between the maxilla’s infratemporal surface and the pterygoid process of the sphenoid
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Is located inferior to the apex of the orbit
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Is located between the infratemporal fossa and the nasal cavity
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Is a major pathway for the spread of infections and tumors from the head and neck into the skull base
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Enables communication between the infratemporal fossa, middle cranial fossa, nasopharynx, nasal cavity, orbit, and oral cavity
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Contains major nerves and vessels:
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Maxillary division of the trigeminal nerve and branches
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Pterygopalatine (sphenopalatine, Meckel’s) ganglion
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3rd part of the maxillary artery and branches (with corresponding veins)
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Clinically, the pterygopalatine fossa is often described as being divided into:
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Anterior (vascular) compartment—location of 3rd part of maxillary a. and its branches
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Posterior (neural) compartment—location of maxillary division of the trigeminal n., pterygopalatine ganglion, and n. of the pterygoid canal
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7 openings (foramina/fissures/canals) allow passage of nerves and vessels

Borders and openings
Borders
Border | Structure(s) | Opening(s) |
---|---|---|
Anterior | Infratemporal surface of the posterior maxilla | |
Posterior | Pterygoid process of the sphenoid |
|
Medial | Perpendicular plate of the palatine | Sphenopalatine foramen |
Lateral | Pterygomaxillary fissure | Pterygomaxillary fissure |
Superior | Inferior surface of the sphenoid and the orbital plate of the palatine bone | Inferior orbital fissure |
Inferior | Pyramidal process of the palatine | Greater palatine canal |
Openings
Opening | Location | Communicates With | Transmitted Structures |
---|---|---|---|
Pterygomaxillary fissure | Lateral part of the pterygopalatine fossa | Infratemporal fossa |
|
Sphenopalatine foramen |
|
Nasal cavity |
|
Inferior orbital fissure |
|
Orbit |
|
Greater palatine canal |
|
Oral cavity |
|
Foramen rotundum | Posterolateral part of the pterygopalatine fossa | Middle cranial fossa | Maxillary division of the trigeminal n. |
Pterygoid (vidian) canal |
|
Middle cranial fossa |
|
Palatovaginal (pharyngeal) canal |
|
Nasopharynx |
|


Contents of the pterygopalatine fossa
Vascular supply
ARTERIAL SUPPLY | ||
Artery | Source | Course |
Maxillary (3rd part) | External carotid a. |
|
Infraorbital | The continuation of the 3rd part of the maxillary a. |
|
Descending palatine | 3rd part of the maxillary a. |
|
Artery of the pterygoid canal |
|
|
Pharyngeal |
|
|
Sphenopalatine |
|

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