Abstract
Background
Restricted mouth opening, which is also known as Limited mouth opening, trismus, or lockjaw, has several causes and Temporomandibular joint disorders are considered as the main cause.
Purpose
This study aimed to retrospectively review the causes of restricted mouth opening due to TMJ and its management.
Study design
A retrospective cohort study of subjects who underwent Management of locked jaw Due to TMJ. A total of 879 consecutive patients with locked jaw in the period from 2016 to 2022 were reviewed for the causative factor and its management.
Main outcome variable(s)
maximum inter-incisal opening (MIO in mm), pain in the TMJ (Yes/No) using the visual analogue score (VAS).
Results
the final sample consisted of 409 patients. Irreducible disc displacement represented 60 % of the total cases (245 patients with mean age 31.7 ± 5.5). Followed by TMJ osteoarthritis which represented 12 % (48 patients with mean age 38.4 ± 8.3), Joint adhesion Secondary to Immobilization (9 %), post-surgical represented 8.5 %, Anchored disc phenomenon (7.5 %). While ankylosis, coronoid hyperplasia, radiotherapy, were represented only 3 % (14 patients). Arthrocentesis with joint injection successfully used in treatment of 394 (96 %). Out of them, 21 patients didn’t respond to the arthrocentesis and treated by second intervention with TMJ arthroscopy level II. 6 patients with TMJ ankylosis treated with Hegab protocol while one patient with failed joint prosthesis was treated with Total joint replacement.
Conclusions
Arthrocentesis with joint injection could be used effectively in most cases of locked jaw secondary to TMJ. While TMJ arthroscopy could be used in un-responded cases.
1
Introduction
Restricted mouth opening or lockjaw is not a disease by itself rather than a manifestation of underlying causes which ranges from simple cause to potentially life-threatening causes [ , ]. Temporomandibular joint (TMJ) disorders represent one of the major causes of restricted mouth opening and the diagnostic imaging play an important role in the evaluation of the causative factor. While MRI is also reliable for the detection of internal derangement, especially for anterior disc displacement with or without reduction, the diagnostic accuracy for evaluating the presence of intra-articular adhesions is rather poor [ , ] .
Causative factor | No of patients | Percentage | Gender | Mean Age | Study Variable | P Value | ||
---|---|---|---|---|---|---|---|---|
128M (31 %) | 281 F (69 %) | Gender | Age | |||||
Irreducible anterior disc displacement | 245 | 60 % | 67 | 178 | 31.7 + 5.5 | Mouth opening (mm) | 0.9088 ns | 0.4722 ns |
Pain (0–10 VAS) | <0.0001 | 0.0278∗ | ||||||
Osteoarthritis | 48 | 12 % | 13 | 35 | 38.4 ± 8.3 | Mouth opening (mm) | 0.0200 | 0.8268 ns |
Pain (0–10 VAS) | 0.0035 | 0.6020 ns | ||||||
Joint adhesion Secondary to Immobilization | 36 | 9 % | 26 | 10 | 31.9 ± 5.5 | Mouth opening (mm) | 0.4259 ns | 0.8977 ns |
Pain (0–10 VAS) | 0.2287 ns | 0.7878 ns | ||||||
Post-surgical | 35 | 8.5 % | 7 | 28 | 32.5 ± 5.6 | Mouth opening (mm) | 0.0218 | 0.0336 |
Pain (0–10 VAS) | 0.3296 ns | 0.1568 ns | ||||||
Anchored disc phenomenon/joint adhesion | 31 | 7.5 % | 9 | 22 | 32.3 ± 4.8 | Mouth opening (mm) | 0.0045 | 0.2710 ns |
Pain (0–10 VAS) | 0.1988 ns | 0.9164 ns | ||||||
Ankylosis | 7 | 3 % | 2 | 5 | 25.4 ± 5.6 | Mouth opening (mm) | 0.1337 ns | 0.8571 ns |
Pain (0–10 VAS) | 0.0347 | 0.2845 ns | ||||||
limitation of mouth opening after radiotherapy | 4 | 4 | – | 55.7 ± 7.4 | Mouth opening (mm) | NA – all Male | 0.8824 ns | |
Pain (0–10 VAS) | NA – all Male | 0.0864 ns | ||||||
Coronoid Hyperplasia | 3 | – | 3 | 39.0 ± 2.6 | Mouth opening (mm) | NA – all Female | 0.8516 ns | |
Pain (0–10 VAS) | NA – all Female | 0.2636 ns |
Causative factor | Management | Variable | Preoperative | at 1M | at 3 M | at 6 M | at 12 M | P-Value | |
---|---|---|---|---|---|---|---|---|---|
DDNR | Arthrocentesis/Arthroscopic Lysis and lavage + joint injection With HA or HA/PRP mix |
MVMO | Mean + SD | 22.4 ± 2.35 | 34.13 + 2.2 | 37.44 + 1.45 | 39.13 + 1.1 | 39.43 ± 1.1 | <0.0001 |
Lower 95 % CI of mean | 22.14 | 33.85 | 37.26 | 38.98 | 39.29 | ||||
Upper 95 % CI of mean | 22.73 | 34.41 | 37.63 | 39.27 | 39.56 | ||||
VAS | Mean + SD | 7.5 ± 0.87 | 3.05 ± 0.86 | 0.43 ± 0.57 | 0.0 ± 0.0 | 0.0 ± 0.0 | <0.0001 | ||
Lower 95 % CI of mean | 7.429 | 2.936 | 0.3605 | 0.0 | 0.0 | ||||
Upper 95 % CI of mean | 7.649 | 3.154 | 0.5048 | 0.0 | 0.0 | ||||
Osteoarthritis | Arthrocentesis Lysis and lavage + joint injection With HA or HA/PRP mix | MVMO | Mean + SD | 24.25 ± 2.1 | 35.04 ± 3.17 | 38.35 ± 2.9 | 39.65 ± 2.5 | 41.69 ± 2.3 | <0.0001 |
Lower 95 % CI of mean | 23.64 | 34.12 | 37.51 | 38.92 | 41.01 | ||||
Upper 95 % CI of mean | 24.86 | 35.96 | 39.20 | 40.38 | 42.37 | ||||
VAS | Mean + SD | 7.87 ± 1.0 | 5.13 ± 2.749 | 2.63 ± 2.11 | 1.00 ± 0.99 | 0.25 ± 0.6 | <0.0001 | ||
Lower 95 % CI of mean | 7.572 | 4.327 | 2.012 | 0.7127 | 0.07537 | ||||
Upper 95 % CI of mean | 8.178 | 5.923 | 3.238 | 1.287 | 0.4246 | ||||
Post-surgical | Arthrocentesis Lysis and lavage with HA/PRP mix (34 patients) – open joint surgery (1 patients) |
MVMO | Mean + SD | 25.60 ± 3.3 | 36.03 ± 2.2 | 38.86 ± 1.7 | 40.63 ± 2.0 | 38.86 ± 2.6 | <0.0001 |
Lower 95 % CI of mean | 24.46 | 35.27 | 38.29 | 39.93 | 37.96 | ||||
Upper 95 % CI of mean | 26.74 | 36.79 | 39.43 | 41.33 | 39.76 | ||||
VAS | Mean + SD | 7.06 ± 1.3 | 2.89 ± 0.83 | 0.31 ± 0.47 | 0.34 ± 0.54 | 1.6 ± 1.3 | <0.0001 | ||
Lower 95 % CI of mean | 6.609 | 2.600 | 0.1525 | 0.1576 | 1.150 | ||||
Upper 95 % CI of mean | 7.505 | 3.172 | 0.4761 | 0.5281 | 2.050 | ||||
Anchored disc phenomenon | Arthrocentesis Lysis and lavage + joint injection with HA |
MVMO | Mean + SD | 22.74 ± 2.35 | 32.35 ± 1.82 | 36.65 ± 1.52 | 38.74 ± 0.99 | 38.74 ± 0.99 | <0.0001 |
Lower 95 % CI of mean | 21.88 | 31.69 | 36.09 | 38.38 | 38.38 | ||||
Upper 95 % CI of mean | 23.60 | 33.02 | 37.20 | 39.11 | 39.11 | ||||
VAS | Mean + SD | 6.9 ± 0.72 | 2.484 ± 057 | 0.13 ± 034 | 0.0 ± 0.0 | 0.0 ± 0.0 | <0.0001 | ||
Lower 95 % CI of mean | 6.607 | 2.275 | 0.004035 | 0.0 | 0.0 | ||||
Upper 95 % CI of mean | 7.134 | 2.693 | 0.2540 | 0.0 | 0.0 | ||||
Joint adhesion Secondary to Immobilization | Arthrocentesis/Arthroscopic Lysis and lavage + joint injection with HA |
MVMO | Mean + SD | 21.69 + 2.08 | 32.97 + 2.65 | 36.61 + 1.48 | 39.06 + 1.41 | 39.11 + 1.41 | <0.0001 |
Lower 95 % CI of mean | 20.99 | 32.08 | 36.11 | 38.58 | 38.63 | ||||
Upper 95 % CI of mean | 22.40 | 33.87 | 37.11 | 39.53 | 39.59 | ||||
VAS | Mean + SD | 6.89 + 0.62 | 2.36 + 0.79 | 0.056 + 0.23 | 0.0 + 0.0 | 0.0 + 0.0 | <0.0001 | ||
Lower 95 % CI of mean | 6.678 | 2.091 | −0.023 | 0.0 | 0.0 | ||||
Upper 95 % CI of mean | 7.099 | 2.631 | 0.134 | 0.0 | 0.0 | ||||
Ankylosis | Hegab Protocol [ ]/Total Joint Replacement | MVMO | Mean + SD | 1.86 + 0.896 | 33.57 + 5.83 | 36.43 + 5.2 | 38.29 + 4.7 | 38.57 + 4.96 | <0.0001 |
Lower 95 % CI of mean | 1.025 | 28.18 | 31.63 | 33.92 | 33.98 | ||||
Upper 95 % CI of mean | 2.689 | 38.96 | 41.23 | 42.65 | 43.16 | ||||
VAS | Mean + SD | 2.3 + 2.6 | 3.86 + 1.95 | 2.57 + 1.7 | 0.86 + 1.5 | 0.7 + 1.5 | 0.0075 | ||
Lower 95 % CI of mean | −0.1445 | 2.052 | 0.9823 | −0.4967 | −0.6693 | ||||
Upper 95 % CI of mean | 4.716 | 5.662 | 4.161 | 2.211 | 2.098 | ||||
limitation of mouth opening after radiotherapy | Release Surgery + Physiotherapy | MVMO | Mean + SD | 21.25 + 4.35 | 26.25 + 2.87 | 29.50 + 1.29 | 33.00 + 0.82 | 34.75 + 1.25 | 0.0694ns |
Lower 95 % CI of mean | 14.33 | 21.68 | 27.45 | 31.70 | 32.75 | ||||
Upper 95 % CI of mean | 28.17 | 30.82 | 31.55 | 34.30 | 36.75 | ||||
VAS | Mean + SD | 8.00 + 0.82 | 6.00 + 0.82 | 4.75 + 1.26 | 4.00 + 0.82 | 4.00 + 0.82 | <0.0001 | ||
Lower 95 % CI of mean | 6.701 | 4.701 | 2.748 | 2.701 | 2.701 | ||||
Upper 95 % CI of mean | 9.299 | 7.299 | 6.752 | 5.299 | 5.299 | ||||
Coronoid Hyperplasia | Coronidectomy + Physiotherapy | MVMO | Mean + SD | 20.67 + 2.56 | 37.33 + 2.08 | 40.00 + 2.00 | 41.67 + 2.89 | 42.67 + 2.52 | <0.0001 |
Lower 95 % CI of mean | 14.42 | 32.16 | 35.03 | 34.50 | 36.42 | ||||
Upper 95 % CI of mean | 26.92 | 42.50 | 44.97 | 48.84 | 48.92 | ||||
VAS | Mean + SD | 2.67 + 1.53 | 1.67 + 0.58 | 0.0 + 0.0 | 0.0 + 0.0 | 0.0 + 0.0 | <0.0001 | ||
Lower 95 % CI of mean | −1.128 | 0.2325 | 0.0 | 0.0 | 0.0 | ||||
Upper 95 % CI of mean | 6.461 | 3.101 | 0.0 | 0.0 | 0.0 |

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