Abstract
Jacob’s disease is a rare condition consisting of pseudojoint formation between enlarged coronoid process and the inner surface of the zygoma. The authors report a 45-year-old female patient who presented with limited mouth opening (5 mm) and swelling of the left zygoma. No temporomandibular joint disease was diagnosed. 3D computed tomography images showed a mushroom-shaped coronoid growth with pseudojoint formation medial and superior to the zygomatic arch. Under general anaesthesia, coronoidectomy was carried out through a combined extraoral and intraoral approach. Histopathological examination revealed normal trabecular bone covered with hyaline cartilage. To the best of the authors’ knowledge this case is the fifth typical mushroom-shaped Jacob’s disease; only four similar cases have been reported. A review of the literature revealed only 39 histologically proved cases of Jacob’s disease cases up to 2010. Aggressive physical treatment was given to improve function and maximum mouth opening, which had increased to 40 mm at 3 months follow-up. The literature concerning this condition’s aetiology, pathogenesis, clinical characteristics, diagnosis, and treatment is reviewed.
Jacob’s disease or osteochondroma of the mandibular coronoid process, is a benign skeletal tumour that is rare in the oral and maxillofacial skeleton and even more rare in the coronoid process. Though first noted by Langenbeck in 1853 as an enlargement of the mandibular coronoid process, the first case report was described by J acob in 1899, who reported a pseudojoint between the coronoid and the zygomatic arch due to an osteochondroma formation of the coronoid process.
A review of the literature revealed only 39 histologically proved cases out of 50 reported cases ( Table 1 ). To the best of the authors’ knowledge this is the second case reported in India and it is the fifth typical mushroom-shaped Jacob’s disease; only four similar cases have been reported. The disease appears to involve males (63%) more often than females at a mean age of 30 years with an age range of 5–73 years. There is slight predilection for involvement of the left coronoid process. Initial signs and symptoms are a feeling of tightness in the joint region and gradual reduction in mouth opening. Later stages show a total trismus and appreciable swelling at the malar prominence. Pain is not a feature of the disease but deformity of the surrounding structures and facial deformity was found in most cases .
Case no | Authors | Year | Gender | Age | Side | Facial asymmetry | Mouth opening in mm | Surgical approach |
---|---|---|---|---|---|---|---|---|
1 | S hackelford & B rown | 1943 | Male | 15 | Left | Present | 12.5 mm | Extraoral |
2 | S hackelford & B rown | 1943 | Male | 19 | Right | Present | 10 mm | Extraoral |
3 | S hackelford & B rown | 1943 | Male | 38 | Right | Present | Reduced | Extraoral |
4 | B randt | 1949 | Female | 37 | Right | Present | 25 mm | Extraoral |
5 | B railsford | 1952 | Male | 29 | Left | Present | ||
6 | H olmes | 1956 | Male | 36 | Left | 8 mm | ||
7 | L evine et al. | 1957 | Female | 73 | Left | Present | 6 mm | |
8 | D ingman & N atvig | 1957 | Male | 27 | Right | 8 mm | Extraoral | |
9 | A ntoni et al. | 1958 | Male | 29 | Left | Present | Adequate | |
10 | P ap & F riedman | 1958 | Male | 13 | Left | Present | 10 mm | Extraoral |
11 | L ebo | 1961 | Male | 18 | Left | 14 mm | Extraoral | |
12 | M ohnac | 1962 | Male | 18 | Right | 18 mm | Extraoral | |
13 | A llan & R eid | 1967 | Female | 32 | Right | 16 mm | Intraoral | |
14 | A llan & R eid | 1967 | Male | 22 | Left | Present | 13 mm | Intraoral |
15 | M eyer | 1972 | Female | 10 | Right | None | 20 mm | Intraoral |
16 | J ames et al. | 1974 | Female | 52 | Right | Present | 5 mm | Extraoral |
17 | C ooper & F inch | 1974 | Female | 43 | Left | None | 6 mm | Intraoral |
18 | T akeda et al. | 1975 | Female | 14 | Left | Present | 10 mm | Extraoral |
19 | S inger & S chultz | 1976 | Male | 64 | Right | Present | 5 mm | Combined |
20 | R amon et al. | 1977 | Male | 45 | Right | Present | Reduced | Combined |
21 | I to et al. | 1981 | Female | 20 | Left | Present | 3 mm | Intraoral |
22 | I shii et al. | 1983 | Female | 32 | Left | Present | 7 mm | Intraoral |
23 | I shii et al. | 1983 | Male | 53 | Right | Present | 20 mm | Combined |
24 | R evington | 1984 | Male | 24 | Right | None | 9 mm | Extraoral |
25 | T ucker et al. | 1984 | Male | 16 | Right | Present | 22 mm | Intraoral |
26 | S chwartz & L iebel | 1987 | Male | 15 | Left | Present | 18 mm | Extraoral |
27 | M acleod | 1987 | Female | 46 | Left | Present | 5 mm | Intraoral |
28 | T otsuka et al. | 1990 | Female | 37 | Left | Present | 2 mm | Intraoral |
29 | A sanami et al. | 1990 | Male | 17 | Left | None | 8 mm | Combined |
30 | K erscher et al. | 1993 | Male | 45 | Left | None | 14 mm | Intraoral |
31 | C onstantinides et al. | 1997 | Male | 31 | Right | Present | 10 mm | Extraoral |
32 | C hen et al. | 1998 | Female | 57 | Left | Present | 14 mm | Extraoral |
33 | M aganaro | 1998 | Female | 26 | Present | |||
34 | C hichareon et al. | 1999 | Male | 5 | Right | Present | ||
35 | H ernandez et al. | 2000 | Male | 22 | Left | Present | 21 mm | Extraoral |
36 | R oychoudhury et al. | 2001 | Male | 32 | Left | Present | 0 mm | Extraoral |
37 | E scuder i de la T orre et al. | 2001 | Female | 24 | Bilateral | Present | Reduced | Intraoral |
38 | E mekli | 2002 | Female | 26 | Right | Present | 10 mm | Intraoral |
39 | E mekli | 2002 | Male | 21 | Right | Present | Reduced | Extraoral |
40 | C apote | 2005 | Female | 23 | Present | Reduced | Intraoral | |
41 | V illanueva | 2006 | Female | 44 | Left | Present | 30 mm | Intraoral |
42 | A kan & M ehreliyeva | 2006 | Male | 24 | Bilateral | None | 15 mm | Intraoral |
43 | D ede | 2007 | Male | 20 | Bilateral | Present | 6 mm | Intraoral |
44 | F erro M artín | 2008 | Male | 28 | Bilateral | Present | 13 mm | Intraoral |
45 | G opikiran | 2009 | Male | 15 | Bilateral | Present | 15 mm | Intraoral |
46 | D’A mbrosio | 2009 | Male | 39 | Reduced | |||
47 | E toz O sman | 2009 | Female | 43 | Right | Present | 14 mm | Intraoral |
48 | Z hong et al. | 2009 | Male | 28 | Left | Present | 13 mm | Intraoral |
49 | W aseem | 2010 | Male | 15 | Right | Present | 10 mm | Intraoral |
50 | A hmet et al. | 2010 | Male | 16 | Right | Present | 7 mm | Extraoral |
51 | K rishna (present case) | 2010 | Female | 45 | Left | Present | 5 mm | Combined |