Background and purpose : Hyperdry amniotic membrane (AM), a novel preservable material derived from the human amnion, has been introduced clinically in ophthalmology and other fields. The aim of this study is to evaluate the safeness and the usefulness in applying to oral surgery.
Materials and methods : Hyperdry AM was prepared as described previously. Fresh human amnions were obtained with the consent donors who were scheduled to undergo cesarean section at our hospital. Hyperdry AM was used in the treatment of surgical soft tissue defects in tumour ablation, vestibuloplasty or palatoplasty.
Results : Hyper AM was used in total 30 patients: 22 patients for tumour ablation, 6 patients for palatoplasty, and 2 patients for vestibuloplasty. The membrane was found to be easy to handle as an oral-dressing material. It adhered well to the bare connective and muscular tissues. No remarkable adverse effects were observed in the process of wound healing.
Conclusions : The results suggested that hyperdry AM is biologically acceptable to oral wounds and could be a suitable clinical alternative for the repair of the oral mucosa.