Aim/Objective/Purpose: Platelet-rich plasma (PRP) is extensively used in oral and maxillofacial surgery to stimulate and accelerate bone healing. However, contradictory results were reported. In order to clarify this inconsistency, this…
Central Giant Cell Lesion is an uncommon benign jaw lesion, with uncertain etiology, and a variable clinical behavior. Studies of molecular markers of CGCL, may help understanding better the nature…
Objective: Animal models offer an unprecedented opportunity to preclinically evaluate the efficacy and safety of newly developed human surgical therapies. In order to develop maxillofacial surgical research including tissue engineering…
Introduction: Stem cells based therapies are the most promising and powerful method to provide patients specific tissue substitutes for the regeneration or reconstruction of tissue and organs. Aim: Using bone…
Introduction: Titanium surface modifications can influence the osseointegration process, the final goal being accelerate bone formation around implants. Purpose: This study aimed at evaluating the effect of Ti surface modification…
Objectives: The aim of this study was to analyze the expression of genes involved in bone remodeling process finding in dental pulp, and in particular the expression of, COL1A1, MMP9…
Introduction: In clinical practice different bone substitute biomaterials are used for maxillary sinus floor augmentation. Due to biocompatibility with living body and bioactivity hydroxyapatite (HAP), tricalcium phosphate (TCP) and biphasic…
Aim: The aim of this study was to evaluate the osteorigenerative properties of AFSc associated with hydroxyapatite, and compare their behaviour with the use of biomaterial in sinus grafts on…
Introduction: Nowadays different manufacturers of bone graft materials are known. Hydroxyapatite and tricalcium phosphate (HAP/TCP) biphasic bone graft materials are the most promoting due to particular biodegradation. Literature data of…
Purpose: Mechanical stress is known to be important for regulation of bone turnover, though the detailed mechanisms are not fully understood. In the present study, we examined the effect of…
Objective: The goal in this study is to investigate the safety of a photodynamic antimicrobial chemotherapy (PACT) protocol, which we have found to be efficient against Porphyromonas gingivalis in a…
Introduction: It has been suggested that nitric oxide (NO) promotes angiogenesis and tumor progression and CXC Chemokine Recepter-4 (CXCR4) is involved in cell migration in cancer metastasis. Efficacy of single…
Purpose: In these latter years, the therapy for osteoporosis (OP) is the most required for the quality of life. Therefore, it is suggested that study for finding a novel osteoporotic…
Purpose: Chemotherapy is an important alternative to surgery and radiation to treat successfully for oral squamous cell carcinoma (OSCC). Although current anticancer drugs are effective and useful, it is important…
Purpose: The purpose of this study was to present the concept and effect of buried magnetic field, comparing results in osseous wound with and without graft. Material and methods: A…
Background: Various types of biocompatible materials have been used to promote bone regeneration. The cellular and molecular activities determining the tissue response and bone formation during the healing of bone…
Introduction: Nanostructured titanium (NTI) indicates improved biological properties supported by a number of biocompatibility test, cell cultivation observations, wettability, surface roughness, surface energy analysis, but there is still no fairly…
Objective: Bax is a pro-apoptotic molecule that functions as a tumor suppressor, and Bax gene therapy is investigated for various tumor cells. Gene transfer by mRNA lipofection is more efficient…
Aim: This study was designed to assess the regenerative process in models of leg lower bone defects in the rats, assessed with the use of in vivo micro-X-ray CT (M-CT:…
Aim: Three different types of silk fibroin (SF) membrane were tested for guided bone regeneration. Materials and method: Physical properties of 3 SF membrane was tested by FT-IR and dissolution…
