Background: Fibula free flap was first described by Taylor in 1975, and applied for mandibular reconstruction by Hidalgo in 1989. His pedicle is based on the peroneal artery and itscomitant…
The population of the United Kingdom is becoming ever more obese, with similar findings demonstrated across the developed world. The incidence of oral and oropharyngeal cancer is also rising. Although…
Purpose: To present our experience with the management of 33 extensive mandibular ameloblastomas treated with segmental mandibulectomy, reconstruction with free fibula or iliac crest flap, and rehabilitation with immediate or…
Introduction: Regular over-ordering of cross-matched blood is expensive and can result in a shortage of available blood. In order to minimize the impact on an already over-stretched transfusion service, the…
Background and objectives: The ALT has become one of the first choices for reconstruction in defects involving the oral cavity and oropharynx. Or aim is to review the indications for…
Introduction: It is recognized that simulation can be used to aid the training of surgeons. Many courses give participants a certificate of completion rather than one of competence or proficiency….
Background and objectives: Reconstruction of jaw defects secondary to resections represents a surgical challenge. Mandibulectomy associated to soft tissues is usually required, bringing different degrees of esthetic and functional alterations….
Background: The benefits of induction chemotherapy in oral squamous cell carcinoma (OSCC) remain to be clearly defined, as trials to date have not shown a major survival benefit when induction…
Oral propranolol (PRN) has recently been shown to be highly effective for infantile hemangiomas (IHs), and is currently recommended as the first-line treatment of complicated IHs. However, no pharmacokinetic parameters…
Objective: To investigate the expression of Transient Receptor Potential Melastatin type 2 (TRPM2) in the human tongue squamous cell carcinoma tissues and SCC cell lines. The effect of activated and…
Purpose: To value the therapeutic effect of PUMA gene mediated by by radiation-inducible promoters in the treatment of Xenograft of human tongue squamous carcinoma in naked mice. Methods: Eukaryotic cell…
Objective: To investigate the effect of overexpression of p53 upregulated modulator of apoptosis (PUMA) gene induced by As-miR-222 transfection on apoptosis of oral squamous cell carcinoma(OSCC). Methods: Tca8113 was treated…
Background and objectives: The most frequent reported cause of treatment failure in early oral tongue cancer is regional recurrence. We analyzed our data from the recent two decades to review…
Introduction: Sentinel node biopsy (SNB) is gaining acceptance as a standard management of early head and neck cancer. Occult nodal metastasis occur in 20–30% of clinically and radiologically N0 necks….
Objectives: The aims of this presentation were to describe the management of a rare case of infantile hemangiopericytoma (HPC) in a newborn girl, to analyze the literature on pediatric cases…
Aim: The aim of study was to investigate the involvement of the submandibular gland in patients with oral cavity squamous cell carcinoma oft the tongue and floor oft the mouth….
Background: There are more than 30 genes polymorphisms associated with risk and survival rate of oral squamous cell carcinoma (OSCC). Nevertheless, different ethnicity could show different genotype and allele as…
Squamous cells carcinoma (SCC) is a malignant neoplasm drift of the squamous epithelium and it’s characteristic is multifactorial etiopathogenesis. Nowadays it’s known that Human Papillomavirus (HPV) is a risk factor,…
Lichen planus is a relatively common disorder, estimated to effect 0.5–2.0% of the general population. It is a chronic inflammatory disease affecting mucosal and cutanous tissue. Various treatment regimens have…
Background and objectives: Gemcitabine (GEM) is a pyrimidine nucleoside analogue that is a new chemotherapeutic agent used for treating various cancers. Because accumulating evidence indicates that GEM may activate host…
