3 Noninfectious Papillary Lesions
Inflammatory Papillary Hyperplasia of the Palate
• Papillary hyperplasia of the palate usually occurs in adults wearing dentures; it is occasionally seen in patients with high-arched palates and mouth-breathing habit (with adenoidal facies); may be sensitive, especially if associated with erythematous candidiasis, because denture may act as a fomite; dryness from mouth-breathing also predisposes to candidiasis (Fig. 3-1).
• There is proliferation of fibrous tissue in nodules with variable lymphoplasmacytic infiltrate; overlying epithelium may be hyperplastic and exhibit spongiosis and leukocyte exocytosis; pseudoepitheliomatous hyperplasia may be seen (Figs. 3-2 to 3-4).
FIGURE 3-2 Inflammatory papillary hyperplasia of palate. A, Papillary proliferation of fibrous tissue and epithelium. B, Fibroepithelial and pseudoepitheliomatous hyperplasia with chronic inflammation. C, Islands of benign epithelial cells.