28: Bone diseases of radiological importance

Bone diseases of radiological importance


There are many diseases and abnormalities of bone. Some are localized to the jaws while others can affect the whole skeleton. It is beyond the scope of this book to consider them all. This chapter summarizes a somewhat diverse, but important group of bone conditions which can affect the facial skeleton and which are of radiological importance.

Unfortunately, several of the bone diseases described, although totally different in nature, can present very similar appearances radiographically. To differentiate them, clinicians need to consider all relevant factors including: the age of the patient, the distribution of the disease (whether it is generalized or localized) and which bones are involved, as well as noting the specific radiographic features.

Using the atlas approach adopted in Chapter 24, an example of each of the conditions is shown together with a summary of the main radiographic features seen in the skull and facial skeleton. It is worth remembering that bone is a constantly changing, dynamic tissue. Thus diseases of bone can present a spectrum of radiographic appearances depending on the behaviour and maturity or stage of the disease and/or lesion(s). The examples shown represent only a small part of that spectrum.

The diseases of bone described include:

Developmental or genetic disorders

Cleidocranial dysplasia

This is a rare developmental disturbance affecting the skull and clavicles. The abnormalities of dentition can be gross but usually affect only the permanent teeth. Examples are delayed eruption and multiple supernumeraries (see Fig. 28.1).

Osteopetrosis (Albers–Schönberg disease)

This hereditary disease is characterized by sclerosis of the skeleton (so called marble bones), fragile bones and secondary anaemia. Bone formation is normal but bone resorption is reduced, resulting in the presence of excessive calcified tissue and lack of marrow space (see Fig. 28.2). Cranial base changes may produce compression of the cranial nerves.

Infective or inflammatory conditions


This spreading, progressive inflammation of bone and bone marrow, more frequently affects the mandible than the maxilla. It is caused usually by local factors such as periapical infection, pericoronitis, acute periodontal lesions, extractions or trauma. The inflammatory response may be acute or chronic depending on the virulence of the infecting organism and the resistance of the patient. It results ultimately in the destruction of the infected bone (see Figs 28.3 and 28.4). The reaction of the surrounding bone and periosteum is very variable and often age-related. There may be surrounding sclerosis of the bone forming poorly defined patchy opacity. Sequestra (small pieces of necrotic bone) can be exfoliated over a period of several weeks. The periosteum around the affected area can lay down new bone (the so-called periosteal reaction). In children this can be pronounced and is described as proliferative periostitis. This typically affects the mandible in young girls, following apical or pericoronal infection associated with the lower first molar producing a non-tender, bony hard swelling of the lower border. Radiographically the proliferative periostitis results in a laminated, so called onion-skin, appearance (see Fig. 28.5).

Jan 12, 2015 | Posted by in Oral and Maxillofacial Radiology | Comments Off on 28: Bone diseases of radiological importance
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