9.4
Vasoconstrictors
- Most local anesthetics cause vasodilation via direct smooth muscle relaxation of arterioles. Vasoconstrictors assist in keeping the local anesthetic in the site longer by reducing vascular uptake
- Cocaine is the only local anesthetic that causes peripheral vasoconstriction
- Types
- Epinephrine
- Most commonly
- 1 : 50 000
- 1 : 100 000 (Figure 9.5)
- 1 : 200 000
- Most commonly
- Levonordefrin – alpha‐methylnorepinephrine
- Most commonly 1 : 20 000
- Epinephrine