The authors present the clinical case of a malignant paraganglioma of the parapharyngeal region: diagnosis, surgery and treatment with radiotherapy, MIBG-I131, chemotherapy and octreotid. 63 year old woman was referred…
Background and objectives: Fatty acid binding protein 4 (FABP4) is an intracellular lipid chaperone molecules that are expressed and involved in functions of adipocyte, macrophage, and dendritic cell. However, little…
Background and objectives: The aim of this study is to examine the effect of Image-guided stereotactic radiotherapy (IGSRT) in the treatment of advanced, recurrent lesions for head and neck carcinoma…
Tumor hypoxia adversely affects clinical radiation response of head and neck squamous cell carcinoma. 18F-fluoromisonidazole positron emission tomography ([F-18]FMISO-PET) offers a noninvasive means of assessing viable hypoxic tissue in tumor….
Background and objectives: Intraoperative frozen section analysis of surgical margins is widely used in head and neck cancer surgery. Their use in management of oral squamous cell carcimoma (SCC) and…
Background and objectives: MicroRNAs (miRNAs) are small non-coding double-stranded RNA with size of approximately 22 nucleotides, and those inhibit protein translation by binding the 3 f-untranslated region of target mRNAs….
Objectives: Since hematogeneous tumor cell dissemination is a key event in tumor progression we assessed the prognostic significance of disseminated tumor cells (DTCs) in BM and circulating tumor cells (CTCs)…
Background and objectives: Recent studies show that interleukin-6 (IL-6) plays a role in tumor development and expansion. However, available information related to the prognostic significance of IL-6 for oral squamous…
Background and objectives: The clinical and radiological detection of persistent or recurrent cervical metastasis is difficult in the early phase after surgery and/or radiotherapy. Computed tomograpy (CT) is used in…
Background and objectives: To study the efficacy Nd:YAG laser in the management of oral leukoplakia. Methods: The study comprises of minimum 20 patients, with clinically diagnosed oral leukoplakia attending the…
Global cancer statistical data show that Central Europe has one of the highest incidence rates of oral cancer worldwide mainly in men’s population. Early detection is extremely important as it…
Introduction: Epidermoid carcinoma of the oral cavity has been classically associated with male patients over the age of 50, with chronic consumption of tobacco, alcohol. In recent years is increasing…
Introduction: Surgery usually is the first step and is an important treatment for oral cancer. Because of pre-existing submucous fibrosis, tissue swelling, and distorted anatomic structure, it is very difficult…
Introduction: There is evidence to suggest that the number, type and location of tumor-infiltrating lymphocytes may be a strong prognostic indicator in colon cancer. The purpose of this preliminary investigation…
Background and objectives: Successful management of maxillofacial lesions follows a specific clinical course: full history and physical exam, radiographic analysis, accurate provisional diagnostic biopsy, and surgical resection enabling accurate final…
Oral squamous cell carcinoma (OSCC) is a common malignancy. The incidence of OSCC is particularly high in some Asian countries because of the popularity of the habit of chewing areca….
Surgery is still the primary choice of treatment for patients with functionally resectable oral cancers. In the past few years however, new treatments such as induction chemotherapy and postoperative chemoradiation…
Objectives: 1. The stage of presentation of oral cancers in Bedfordshire, UK; 2. The treatment these patients received; 3. And analysis of outcome of treatment including recurrence and survival. Methods:…
Objective: Increased experience in sinus lifting procedures has led to a number of literature reports, but the potential effects of sinus lifting on voice quality is not clearly addressed in…
Introduction: This study examines 10-year treatment outcomes in this patient population over the time-span of the changing treatment paradigm. Methods: A cohort of 290 patients was followed for 344 months…
