4.3Substance Use Disorder Treatment
- Consider coordinating with the pain and/or rehabilitation doctor and surgeon to establish a plan regarding adjusting substance use disorder medications for an elective procedure, balancing the risk between relapse, perioperative complications, and/or pain control in the perioperative period
- Among medical specialties, anesthesiologists tend to have a higher rate of substance abuse likely related to a stressful environment and ease of diversion [12]
Varenicline
- Treatment for nicotine abuse
- Mechanism of Action
- Partial nicotinic receptor agonist
- Clinical Implications
- Continue drug perioperatively
- Chronic exposure may lead to negative cardiovascular effects [13]
Acamprosate
- Treatment for alcohol abuse
- Mechanism of Action
- Not well established
- Clinical Implications
- Continue drug perioperatively
Disulfiram
- Treatment for alcohol abuse
- Mechanism of Action (Figure 4.7

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