The defects of the face are often complex and extensive whose the aetiology is essentially malignant. They constitute a challenge to which is frequently confronted the Maxillofacial surgeon. Reconstructive surgery is always the solution where morphological and functional rehabilitation of the face involves many autoplasties. Indeed the restoration of the defect by autologous tissue is the ideal solution in condition to respect the basic principles of aesthetic units and subunits of the face. The indications are based on the criteria of location of the defect, size and quality of local tissues, but also on age, general condition and the aetiology of the defect. The progress of musculocutaneous flaps and particularly microvascular transplants have changed radically the data of the surgery of the face. We present here some procedures of repair according to different regions of the face affected by emphasizing the principles of reconstructive surgery of the face.